Search Results

Overview

Uniprot IDQ9BVI4
Protein NameNucleolar complex protein 4 homolog
Gene NameNOC4L
OrganismHomo sapiens

Kla Sites from experimental identification

Position Flanking peptide
138 AHPLEKSKWEGNYLF

Function

No function data available.

Protein Sequence

10 MEREPGAAGV 20 RRALGRRLEA 30 VLASRSEANA 40 VFDILAVLQS 50 EDQEEIQEAV 60 RTCSRLFGAL 70 LERGELFVGQ 80 LPSEEMVMTG 90 SQGATRKYKV 100 WMRHRYHSCC 110 NRLGELLGHP 120 SFQVKELALS 130 ALLKFVQLEG 140 AHPLEKSKWE 150 GNYLFPRELF 160 KLVVGGLLSP 170 EEDQSLLLSQ 180 FREYLDYDDT 190 RYHTMQAAVD 200 AVARVTGQHP 210 EVPPAFWNNA 220 FTLLSAVSLP 230 RREPTVSSFY 240 VKRAELWDTW 250 KVAHLKEHRR 260 VFQAMWLSFL 270 KHKLPLSLYK 280 KVLLIVHDAI 290 LPQLAQPTLM 300 IDFLTRACDL 310 GGALSLLALN 320 GLFILIHKHN 330 LEYPDFYRKL 340 YGLLDPSVFH 350 VKYRARFFHL 360 ADLFLSSSHL 370 PAYLVAAFAK 380 RLARLALTAP 390 PEALLMVLPF 400 ICNLLRRHPA 410 CRVLVHRPHG 420 PELDADPYDP 430 GEEDPAQSRA 440 LESSLWELQA 450 LQRHYHPEVS 460 KAASVINQAL 470 SMPEVSIAPL 480 LELTAYEIFE 490 RDLKKKGPEP 500 VPLEFIPAQG 510 LLGRPGELCA QHFTLS

Gene Ontology

Classification GO ID Description
Cellular Component GO:0030692 Noc4p-Nop14p complex
Cellular Component GO:0031965 nuclear membrane
Cellular Component GO:0005730 nucleolus
Cellular Component GO:0005654 nucleoplasm
Cellular Component GO:0032040 small-subunit processome
Molecular Function GO:0003723 RNA binding
Biological Process GO:0030490 maturation of SSU-rRNA
Biological Process GO:0006364 rRNA processing

Reference

[1] Yang Z, Yan C, Ma J, Peng P, Ren X et al.. Lactylome analysis suggests lactylation-dependent mechanisms of metabolic adaptation in hepatocellular carcinoma.. Nat Metab 5(1):61-79. 2023 Jan. PMID: 36593272.

[2] Bao Q, Wan N, He Z, Cao J, Yuan W et al.. Subcellular Proteomic Mapping of Lysine Lactylation.. J Am Soc Mass Spectrom 35(12):3221-3232. 2024 Dec 4. PMID: 39569522.

[3] He J, Lai T, Zhou Z, Yang H, Lei Z et al.. Multiomics profiling reveals the involvement of protein lactylation in nonhomologous end joining pathway conferring radioresistance in lung adenocarcinoma cell.. Sci Rep 15(1):24651. 2025 Jul 9. PMID: 40634431.

[4] Wu Q, Li Z, Gong T, Zheng X, Zhou X et al.. Porphyromonas gingivalis infection induces lysine lactylation reprogramming in human umbilical vein endothelial cells.. Front Cell Infect Microbiol 16:1706727. 2026. PMID: 41696360.