Search Results
Overview
| Uniprot ID | Q9BW19 |
|---|---|
| Protein Name | Kinesin-like protein KIFC1 |
| Gene Name | KIFC1 |
| Organism | Homo sapiens |
Kla Sites from experimental identification
| Position | Flanking peptide |
|---|---|
| 107 | ATGLKNQKPVPAVPV |
| 18 | VKGNIELKRPLIKAP |
| 479 | LLATGTRKGQGGECE |
| 61 | RGLGATTKITTSHPR |
| 86 | QGQTTAQKVSKKTGP |
| 89 | TTAQKVSKKTGPRCS |
Function
Minus end-directed microtubule-dependent motor required for bipolar spindle formation (PubMed:15843429). May contribute to movement of early endocytic vesicles (By similarity). Regulates cilium formation and structure (By similarity)
Protein Sequence
10
MDPQRSPLLE
20
VKGNIELKRP
30
LIKAPSQLPL
40
SGSRLKRRPD
50
QMEDGLEPEK
60
KRTRGLGATT
70
KITTSHPRVP
80
SLTTVPQTQG
90
QTTAQKVSKK
100
TGPRCSTAIA
110
TGLKNQKPVP
120
AVPVQKSGTS
130
GVPPMAGGKK
140
PSKRPAWDLK
150
GQLCDLNAEL
160
KRCRERTQTL
170
DQENQQLQDQ
180
LRDAQQQVKA
190
LGTERTTLEG
200
HLAKVQAQAE
210
QGQQELKNLR
220
ACVLELEERL
230
STQEGLVQEL
240
QKKQVELQEE
250
RRGLMSQLEE
260
KERRLQTSEA
270
ALSSSQAEVA
280
SLRQETVAQA
290
ALLTEREERL
300
HGLEMERRRL
310
HNQLQELKGN
320
IRVFCRVRPV
330
LPGEPTPPPG
340
LLLFPSGPGG
350
PSDPPTRLSL
360
SRSDERRGTL
370
SGAPAPPTRH
380
DFSFDRVFPP
390
GSGQDEVFEE
400
IAMLVQSALD
410
GYPVCIFAYG
420
QTGSGKTFTM
430
EGGPGGDPQL
440
EGLIPRALRH
450
LFSVAQELSG
460
QGWTYSFVAS
470
YVEIYNETVR
480
DLLATGTRKG
490
QGGECEIRRA
500
GPGSEELTVT
510
NARYVPVSCE
520
KEVDALLHLA
530
RQNRAVARTA
540
QNERSSRSHS
550
VFQLQISGEH
560
SSRGLQCGAP
570
LSLVDLAGSE
580
RLDPGLALGP
590
GERERLRETQ
600
AINSSLSTLG
610
LVIMALSNKE
620
SHVPYRNSKL
630
TYLLQNSLGG
640
SAKMLMFVNI
650
SPLEENVSES
660
LNSLRFASKV
670
NQCVIGTAQA
NRK
Gene Ontology
| Classification | GO ID | Description |
|---|---|---|
| Cellular Component | GO:0005813 | centrosome |
| Cellular Component | GO:0005737 | cytoplasm |
| Cellular Component | GO:0005769 | early endosome |
| Cellular Component | GO:0005871 | kinesin complex |
| Cellular Component | GO:0016020 | membrane |
| Cellular Component | GO:0005874 | microtubule |
| Cellular Component | GO:0005815 | microtubule organizing center |
| Cellular Component | GO:0072686 | mitotic spindle |
| Cellular Component | GO:0005634 | nucleus |
| Molecular Function | GO:0005524 | ATP binding |
| Molecular Function | GO:0016887 | ATP hydrolysis activity |
| Molecular Function | GO:0008017 | microtubule binding |
| Molecular Function | GO:0003777 | microtubule motor activity |
| Biological Process | GO:0051301 | cell division |
| Biological Process | GO:0007018 | microtubule-based movement |
| Biological Process | GO:0007080 | mitotic metaphase chromosome alignment |
| Biological Process | GO:0000070 | mitotic sister chromatid segregation |
| Biological Process | GO:0090307 | mitotic spindle assembly |
| Biological Process | GO:0007283 | spermatogenesis |
Reference
[1] Wu Q, Li Z, Gong T, Zheng X, Zhou X et al.. Porphyromonas gingivalis infection induces lysine lactylation reprogramming in human umbilical vein endothelial cells.. Front Cell Infect Microbiol 16:1706727. 2026. PMID: 41696360.