Search Results
Overview
| Uniprot ID | Q9BW71 |
|---|---|
| Protein Name | HIRA-interacting protein 3 |
| Gene Name | HIRIP3 |
| Organism | Homo sapiens |
Kla Sites from experimental identification
| Position | Flanking peptide |
|---|---|
| 184 | VKKQAPGKASVSRKQ |
| 77 | EDKLDLTKKGKRPPT |
Function
Histone chaperone that carries a H2A-H2B histone complex and facilitates its deposition onto chromatin
Protein Sequence
10
MAREKEMQEF
20
TRSFFRGRPD
30
LSTLTHSIVR
40
RRYLAHSGRS
50
HLEPEEKQAL
60
KRLVEEELLK
70
MQVDEAASRE
80
DKLDLTKKGK
90
RPPTPCSDPE
100
RKRFRFNSES
110
ESGSEASSPD
120
YFGPPAKNGV
130
AAEVSPAKEE
140
NPRRASKAVE
150
ESSDEERQRD
160
LPAQRGEESS
170
EEEEKGYKGK
180
TRKKPVVKKQ
190
APGKASVSRK
200
QAREESEESE
210
AEPVQRTAKK
220
VEGNKGTKSL
230
KESEQESEEE
240
ILAQKKEQRE
250
EEVEEEEKEE
260
DEEKGDWKPR
270
TRSNGRRKSA
280
REERSCKQKS
290
QAKRLLGDSD
300
SEEEQKEAAS
310
SGDDSGRDRE
320
PPVQRKSEDR
330
TQLKGGKRLS
340
GSSEDEEDSG
350
KGEPTAKGSR
360
KMARLGSTSG
370
EESDLEREVS
380
DSEAGGGPQG
390
ERKNRSSKKS
400
SRKGRTRSSS
410
SSSDGSPEAK
420
GGKAGSGRRG
430
EDHPAVMRLK
440
RYIRACGAHR
450
NYKKLLGSCC
460
SHKERLSILR
470
AELEALGMKG
480
TPSLGKCRAL
490
KEQREEAAEV
500
ASLDVANIIS
510
GSGRPRRRTA
520
WNPLGEAAPP
530
GELYRRTLDS
540
DEERPRPAPP
550
DWSHMRGIIS
SDGESN
Gene Ontology
| Classification | GO ID | Description |
|---|---|---|
| Cellular Component | GO:0005730 | nucleolus |
| Cellular Component | GO:0005654 | nucleoplasm |
| Cellular Component | GO:0005634 | nucleus |
| Molecular Function | GO:0000511 | H2A-H2B histone complex chaperone activity |
| Biological Process | GO:0006325 | chromatin organization |
Reference
[1] Hong H, Chen X, Wang H, Gu X, Yuan Y et al.. Global profiling of protein lysine lactylation and potential target modified protein analysis in hepatocellular carcinoma.. Proteomics 23(9):e2200432. 2023 May. PMID: 36625413.
[2] He C, Zhang J, Bai X, Lu C, Zhang K. Lysine lactylation-based insight to understanding the characterization of cervical cancer.. Biochim Biophys Acta Mol Basis Dis 1870(7):167356. 2024 Oct. PMID: 39025375.