Search Results
Overview
| Uniprot ID | Q9BWG6 |
|---|---|
| Protein Name | Sodium channel modifier 1 |
| Gene Name | SCNM1 |
| Organism | Homo sapiens |
Kla Sites from experimental identification
| Position | Flanking peptide |
|---|---|
| 18 | SQLNVLKKRRVGDLL |
Function
As a component of the minor spliceosome, involved in the splicing of U12-type introns in pre-mRNAs (PubMed:36084634). Plays a role in the regulation of primary cilia length and Hedgehog signaling (PubMed:36084634)
Protein Sequence
10
MSFKREGDDW
20
SQLNVLKKRR
30
VGDLLASYIP
40
EDEALMLRDG
50
RFACAICPHR
60
PVLDTLAMLT
70
AHRAGKKHLS
80
SLQLFYGKKQ
90
PGKERKQNPK
100
HQNELRREET
110
KAEAPLLTQT
120
RLITQSALHR
130
APHYNSCCRR
140
KYRPEAPGPS
150
VSLSPMPPSE
160
VKLQSGKISR
170
EPEPAAGPQA
180
EESATVSAPA
190
PMSPTRRRAL
200
DHYLTLRSSG
210
WIPDGRGRWV
220
KDENVEFDSD
230
EEEPPDLPLD
Gene Ontology
| Classification | GO ID | Description |
|---|---|---|
| Cellular Component | GO:0016607 | nuclear speck |
| Cellular Component | GO:0005634 | nucleus |
| Cellular Component | GO:0005681 | spliceosomal complex |
| Molecular Function | GO:0019899 | enzyme binding |
| Molecular Function | GO:0008270 | zinc ion binding |
| Biological Process | GO:0000380 | alternative mRNA splicing, via spliceosome |
| Biological Process | GO:0000398 | mRNA splicing, via spliceosome |
| Biological Process | GO:0008380 | RNA splicing |
| Biological Process | GO:0000388 | spliceosome conformational change to release U4 (or U4atac) and U1 (or U11) |
Reference
PMID: N/A