Search Results
Overview
| Uniprot ID | Q9BXF9 |
|---|---|
| Protein Name | Tektin-3 |
| Gene Name | TEKT3 |
| Organism | Homo sapiens |
Kla Sites from experimental identification
| Position | Flanking peptide |
|---|---|
| 137 | DKYQQTRKTQADTTQ |
| 270 | TAYRIDDKCHHLRNT |
| 360 | ETADAKNKIQTHLAK |
Function
Microtubule inner protein (MIP) part of the dynein-decorated doublet microtubules (DMTs) in cilia and flagellar axoneme (PubMed:36191189). Forms filamentous polymers in the walls of ciliary and flagellar microtubules (By similarity). Required for normal sperm mobility (By similarity)
Protein Sequence
10
MERVGCTLTT
20
TYAHPRPTPT
30
NFLPAISTMA
40
SSYRDRFPHS
50
NLTHSLSLPW
60
RPSTYYKVAS
70
NSPSVAPYCT
80
RSQRVSENTM
90
LPFVSNRTTF
100
FTRYTPDDWY
110
RSNLTNYQES
120
NTSRHNSEKL
130
RVDTSRLIQD
140
KYQQTRKTQA
150
DTTQNLGERV
160
NDIGFWKSEI
170
IHELDEMIGE
180
TNALTDVKKR
190
LERALMETEA
200
PLQVARECLF
210
HREKRMGIDL
220
VHDEVEAQLL
230
TEVDTILCCQ
240
ERMKLHLDKA
250
IAQLAANRAS
260
QHELEKDLSD
270
KQTAYRIDDK
280
CHHLRNTSDG
290
VGYFRGVERV
300
DATVSVPESW
310
AKFTDDNILR
320
SQSERAASAK
330
LRDDIENLLV
340
VTANEMWNQF
350
NKVNLSFTNR
360
IAETADAKNK
370
IQTHLAKTLQ
380
EIFQTEMTIE
390
SIKKAIKDKT
400
AFLKVAQTRL
410
DERTRRPNIE
420
LCRDMAQLRL
430
VNEVHEVDDT
440
IQTLQQRLRD
450
AEDTLQSLVH
460
IKATLEYDLA
470
VKANSLYIDQ
480
EKCMSMRKSY
490
PNTLRLVGFC
Gene Ontology
| Classification | GO ID | Description |
|---|---|---|
| Cellular Component | GO:0002080 | acrosomal membrane |
| Cellular Component | GO:0001669 | acrosomal vesicle |
| Cellular Component | GO:0160111 | axonemal A tubule inner sheath |
| Cellular Component | GO:0005879 | axonemal microtubule |
| Cellular Component | GO:0070062 | extracellular exosome |
| Cellular Component | GO:0015630 | microtubule cytoskeleton |
| Cellular Component | GO:0005634 | nucleus |
| Cellular Component | GO:0002081 | outer acrosomal membrane |
| Cellular Component | GO:0097229 | sperm end piece |
| Cellular Component | GO:0036126 | sperm flagellum |
| Cellular Component | GO:0097225 | sperm midpiece |
| Cellular Component | GO:0097228 | sperm principal piece |
| Biological Process | GO:0060271 | cilium assembly |
| Biological Process | GO:0060294 | cilium movement involved in cell motility |
| Biological Process | GO:0030317 | flagellated sperm motility |
| Biological Process | GO:0060378 | regulation of brood size |
Reference
[1] Yan M, Tu H, Tang S, Gai Z, Shi Q et al.. Lactylated Proteomic Analysis Reveals Functional Implications of Lysine Lactylation In Asthenozoospermia.. Mol Cell Proteomics 24(12):101439. 2025 Dec. PMID: 41192556.