Search Results
Overview
| Uniprot ID | Q9BXS6 |
|---|---|
| Protein Name | Nucleolar and spindle-associated protein 1 |
| Gene Name | NUSAP1 |
| Organism | Homo sapiens |
Kla Sites from experimental identification
| Position | Flanking peptide |
|---|---|
| 176 | SSKPGKNKRTAITTP |
| 267 | SQSTLGLKGSLKRSA |
| 279 | RSAISAAKTGVRFSA |
| 299 | EHKRSLTKTPARKSA |
| 327 | VLGTHKLKTITGNSA |
Function
Microtubule-associated protein with the capacity to bundle and stabilize microtubules (By similarity). May associate with chromosomes and promote the organization of mitotic spindle microtubules around them
Protein Sequence
10
MIIPSLEELD
20
SLKYSDLQNL
30
AKSLGLRANL
40
RATKLLKALK
50
GYIKHEARKG
60
NENQDESQTS
70
ASSCDETEIQ
80
ISNQEEAERQ
90
PLGHVTKTRR
100
RCKTVRVDPD
110
SQQNHSEIKI
120
SNPTEFQNHE
130
KQESQDLRAT
140
AKVPSPPDEH
150
QEAENAVSSG
160
NRDSKVPSEG
170
KKSLYTDESS
180
KPGKNKRTAI
190
TTPNFKKLHE
200
AHFKEMESID
210
QYIERKKKHF
220
EEHNSMNELK
230
QQPINKGGVR
240
TPVPPRGRLS
250
VASTPISQRR
260
SQGRSCGPAS
270
QSTLGLKGSL
280
KRSAISAAKT
290
GVRFSAATKD
300
NEHKRSLTKT
310
PARKSAHVTV
320
SGGTPKGEAV
330
LGTHKLKTIT
340
GNSAAVITPF
350
KLTTEATQTP
360
VSNKKPVFDL
370
KASLSRPLNY
380
EPHKGKLKPW
390
GQSKENNYLN
400
QHVNRINFYK
410
KTYKQPHLQT
420
KEEQRKKREQ
430
ERKEKKAKVL
440
GMRRGLILAE
D
Gene Ontology
| Classification | GO ID | Description |
|---|---|---|
| Cellular Component | GO:0005694 | chromosome |
| Cellular Component | GO:0005737 | cytoplasm |
| Cellular Component | GO:0005874 | microtubule |
| Cellular Component | GO:0072686 | mitotic spindle |
| Cellular Component | GO:0005730 | nucleolus |
| Molecular Function | GO:0003677 | DNA binding |
| Molecular Function | GO:0008017 | microtubule binding |
| Molecular Function | GO:0003723 | RNA binding |
| Biological Process | GO:0040001 | establishment of mitotic spindle localization |
| Biological Process | GO:0007076 | mitotic chromosome condensation |
| Biological Process | GO:0000281 | mitotic cytokinesis |
| Biological Process | GO:0000070 | mitotic sister chromatid segregation |
| Biological Process | GO:0045840 | positive regulation of mitotic nuclear division |
Reference
[1] He C, Zhang J, Bai X, Lu C, Zhang K. Lysine lactylation-based insight to understanding the characterization of cervical cancer.. Biochim Biophys Acta Mol Basis Dis 1870(7):167356. 2024 Oct. PMID: 39025375.
[2] Wu Q, Li Z, Gong T, Zheng X, Zhou X et al.. Porphyromonas gingivalis infection induces lysine lactylation reprogramming in human umbilical vein endothelial cells.. Front Cell Infect Microbiol 16:1706727. 2026. PMID: 41696360.