Search Results
Overview
| Uniprot ID | Q9BXV9 |
|---|---|
| Protein Name | EKC/KEOPS complex subunit GON7 |
| Gene Name | GON7 |
| Organism | Homo sapiens |
Kla Sites from experimental identification
| Position | Flanking peptide |
|---|---|
| 94 | NFDGPSAKRPKTPS* |
Function
Component of the EKC/KEOPS complex that is required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine (PubMed:27903914, PubMed:31481669). The complex is probably involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37 (PubMed:27903914, PubMed:31481669). GON7 plays a supporting role to the catalytic subunit OSGEP in the complex (PubMed:27903914, PubMed:31481669)
Protein Sequence
10
MELLGEYVGQ
20
EGKPQKLRVS
30
CEAPGDGDPF
40
QGLLSGVAQM
50
KDMVTELFDP
60
LVQGEVQHRV
70
AAAPDEDLDG
80
DDEDDAEDEN
90
NIDNRTNFDG
100
PSAKRPKTPS
Gene Ontology
| Classification | GO ID | Description |
|---|---|---|
| Cellular Component | GO:0000408 | EKC/KEOPS complex |
| Cellular Component | GO:0005730 | nucleolus |
| Cellular Component | GO:0005654 | nucleoplasm |
| Cellular Component | GO:0005634 | nucleus |
| Biological Process | GO:1990145 | maintenance of translational fidelity |
| Biological Process | GO:0002949 | tRNA threonylcarbamoyladenosine modification |
Reference
PMID: N/A