Search Results

Overview

Uniprot IDQ9BYV8
Protein NameCentrosomal protein of 41 kDa
Gene NameCEP41
OrganismHomo sapiens

Kla Sites from experimental identification

Position Flanking peptide
290 ARKRSSPKGPPLPAE

Function

Required during ciliogenesis for tubulin glutamylation in cilium. Probably acts by participating in the transport of TTLL6, a tubulin polyglutamylase, between the basal body and the cilium

Protein Sequence

10 MSLRRHIGNP 20 EYLMKRIPQN 30 PRYQHIKSRL 40 DTGNSMTKYT 50 EKLEEIKKNY 60 RYKKDELFKR 70 LKVTTFAQLI 80 IQVASLSDQT 90 LEVTAEEIQR 100 LEDNDSAASD 110 PDAETTARTN 120 GKGNPGEQSP 130 SPEQFINNAG 140 AGDSSRSTLQ 150 SVISGVGELD 160 LDKGPVKKAE 170 PHTKDKPYPD 180 CPFLLLDVRD 190 RDSYQQCHIV 200 GAYSYPIATL 210 SRTMNPYSND 220 ILEYKNAHGK 230 IIILYDDDER 240 LASQAATTMC 250 ERGFENLFML 260 SGGLKVLAQK 270 FPEGLITGSL 280 PASCQQALPP 290 GSARKRSSPK 300 GPPLPAENKW 310 RFTPEDLKKI 320 EYYLEEEQGP 330 ADHPSRLNQA 340 NSSGRESKVP 350 GARSAQNLPG 360 GGPASHSNPR 370 SLSSGHLQGK PWK

Gene Ontology

Classification GO ID Description
Cellular Component GO:0005814 centriole
Cellular Component GO:0005813 centrosome
Cellular Component GO:0036064 ciliary basal body
Cellular Component GO:0005929 cilium
Cellular Component GO:0005829 cytosol
Cellular Component GO:0016020 membrane
Biological Process GO:0060271 cilium assembly
Biological Process GO:0018095 protein polyglutamylation
Biological Process GO:0015031 protein transport

Reference

[1] He J, Lai T, Zhou Z, Yang H, Lei Z et al.. Multiomics profiling reveals the involvement of protein lactylation in nonhomologous end joining pathway conferring radioresistance in lung adenocarcinoma cell.. Sci Rep 15(1):24651. 2025 Jul 9. PMID: 40634431.