Search Results

Overview

Uniprot IDQ9BZW7
Protein NameTestis-specific gene 10 protein
Gene NameTSGA10
OrganismHomo sapiens

Kla Sites from experimental identification

Position Flanking peptide
197 ESELGRQKAENNSLR
212 LLYENTEKDLSDTQR
225 QRHLAKKKYELQLTQ
241 KIMCLDEKIDNFTRQ
27 NCDVELLKTTTRDRE
279 CLQACLDKKSENIAS
296 ESLAMKEKTISGMKN
386 HNELNDIKQKVQDTN
42 ELKCMLEKYERHLAE

Function

Plays a role in spermatogenesis (PubMed:28905369). When overexpressed, prevents nuclear localization of HIF1A (By similarity)

Protein Sequence

10 MMRSRSKSPR 20 RPSPTARGAN 30 CDVELLKTTT 40 RDREELKCML 50 EKYERHLAEI 60 QGNVKVLKSE 70 RDKIFLLYEQ 80 AQEEITRLRR 90 EMMKSCKSPK 100 STTAHAILRR 110 VETERDVAFT 120 DLRRMTTERD 130 SLRERLKIAQ 140 ETAFNEKAHL 150 EQRIEELECT 160 VHNLDDERME 170 QMSNMTLMKE 180 TISTVEKEMK 190 SLARKAMDTE 200 SELGRQKAEN 210 NSLRLLYENT 220 EKDLSDTQRH 230 LAKKKYELQL 240 TQEKIMCLDE 250 KIDNFTRQNI 260 AQREEISILG 270 GTLNDLAKEK 280 ECLQACLDKK 290 SENIASLGES 300 LAMKEKTISG 310 MKNIIAEMEQ 320 ASRQCTEALI 330 VCEQDVSRMR 340 RQLDETNDEL 350 AQIARERDIL 360 AHDNDNLQEQ 370 FAKAKQENQA 380 LSKKLNDTHN 390 ELNDIKQKVQ 400 DTNLEVNKLK 410 NILKSEESEN 420 RQMMEQLRKA 430 NEDAENWENK 440 ARQSEADNNT 450 LKLELITAEA 460 EGNRLKEKVD 470 SLNREVEQHL 480 NAERSYKSQI 490 STLHKSVVKM 500 EEELQKVQFE 510 KVSALADLSS 520 TRELCIKLDS 530 SKELLNRQLV 540 AKDQEIEMRE 550 NELDSAHSEI 560 ELLRSQMANE 570 RISMQNLEAL 580 LVANRDKEYQ 590 SQIALQEKES 600 EIQLLKEHLC 610 LAENKMAIQS 620 RDVAQFRNVV 630 TQLEADLDIT 640 KRQLGTERFE 650 RERAVQELRR 660 QNYSSNAYHM 670 SSTMKPNTKC 680 HSPERAHHRS 690 PDRGLDRSLE ENLCYRDF

Gene Ontology

Classification GO ID Description
Cellular Component GO:0005814 centriole
Cellular Component GO:0005737 cytoplasm
Cellular Component GO:0031514 motile cilium
Cellular Component GO:0043005 neuron projection
Cellular Component GO:0035686 sperm fibrous sheath
Cellular Component GO:0097228 sperm principal piece
Biological Process GO:0007283 spermatogenesis

Reference

[1] Cheng Z, Huang H, Li M, Chen Y. Proteomic analysis identifies PFKP lactylation in SW480 colon cancer cells.. iScience 27(1):108645. 2024 Jan 19. PMID: 38155775.

[2] Yan M, Tu H, Tang S, Gai Z, Shi Q et al.. Lactylated Proteomic Analysis Reveals Functional Implications of Lysine Lactylation In Asthenozoospermia.. Mol Cell Proteomics 24(12):101439. 2025 Dec. PMID: 41192556.