Search Results
Overview
| Uniprot ID | Q9BZX4 |
|---|---|
| Protein Name | Ropporin-1B |
| Gene Name | ROPN1B |
| Organism | Homo sapiens |
Kla Sites from experimental identification
| Position | Flanking peptide |
|---|---|
| 19 | PELPKMLKEFAKAAI |
| 23 | KMLKEFAKAAIRAQP |
Function
Important for male fertility. With ROPN1L, involved in fibrous sheath integrity and sperm motility, plays a role in PKA-dependent signaling processes required for spermatozoa capacitation
Protein Sequence
10
MAQTDKPTCI
20
PPELPKMLKE
30
FAKAAIRAQP
40
QDLIQWGADY
50
FEALSRGETP
60
PVRERSERVA
70
LCNWAELTPE
80
LLKILHSQVA
90
GRLIIRAEEL
100
AQMWKVVNLP
110
TDLFNSVMNV
120
GRFTEEIEWL
130
KFLALACSAL
140
GVTITKTLKI
150
VCEVLSCDHN
160
GGLPRIPFST
170
FQFLYTYIAE
180
VDGEICASHV
190
SRMLNYIEQE
200
VIGPDGLITV
210
NDFTQNPRVW
LE
Gene Ontology
| Classification | GO ID | Description |
|---|---|---|
| Cellular Component | GO:0005737 | cytoplasm |
| Cellular Component | GO:0031514 | motile cilium |
| Molecular Function | GO:0046982 | protein heterodimerization activity |
| Molecular Function | GO:0030159 | signaling receptor complex adaptor activity |
| Biological Process | GO:0007340 | acrosome reaction |
| Biological Process | GO:0098609 | cell-cell adhesion |
| Biological Process | GO:0044782 | cilium organization |
| Biological Process | GO:0061640 | cytoskeleton-dependent cytokinesis |
| Biological Process | GO:0030317 | flagellated sperm motility |
| Biological Process | GO:0007342 | fusion of sperm to egg plasma membrane involved in single fertilization |
| Biological Process | GO:0061512 | protein localization to cilium |
| Biological Process | GO:0007266 | Rho protein signal transduction |
| Biological Process | GO:0048240 | sperm capacitation |
| Biological Process | GO:0007283 | spermatogenesis |
Reference
[1] Yan M, Tu H, Tang S, Gai Z, Shi Q et al.. Lactylated Proteomic Analysis Reveals Functional Implications of Lysine Lactylation In Asthenozoospermia.. Mol Cell Proteomics 24(12):101439. 2025 Dec. PMID: 41192556.