Search Results

Overview

Uniprot ID	Q9CPP6
Protein Name	NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 5
Gene Name	Ndufa5
Organism	Mus musculus

Kla Sites from experimental identification

Position	Flanking peptide
40	DILKHFPKHAAYRKY
46	PKHAAYRKYTEQITN
55	TEQITNEKLDMVKAE
60	NEKLDMVKAEPDVKK

Function

Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that is believed not to be involved in catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone

Protein Sequence

10 MAGLLKKTTG 20 LVGLAVCDTP 30 HERLTILYTK 40 TLDILKHFPK 50 HAAYRKYTEQ 60 ITNEKLDMVK 70 AEPDVKKLEA 80 LLQGGEVEEV 90 ILQAEKELSL 100 ARKMLKWKPW 110 EPLVEEPPAN QWKWPI

Gene Ontology

Classification	GO ID	Description
Cellular Component	GO:0005743	mitochondrial inner membrane
Cellular Component	GO:0005739	mitochondrion
Cellular Component	GO:0032991	protein-containing complex
Cellular Component	GO:0045271	respiratory chain complex I
Biological Process	GO:0009060	aerobic respiration
Biological Process	GO:0042776	proton motive force-driven mitochondrial ATP synthesis
Biological Process	GO:0022904	respiratory electron transport chain

Reference

[1] Chang J, Wu W, Qian P, Lu Z, He X et al.. Multi-omics study on the effect of moderate-intensity exercise on protein lactylation in mouse muscle tissue.. Front Cell Dev Biol 12:1472338. 2024. PMID: 39935788.

[2] Zhuo W, Zhang M, Tan J, Gao Y, Wang Y et al.. Lysine lactylation analysis of proteins in the heart of the Kawasaki disease mouse model.. Front Cell Dev Biol 13:1550220. 2025. PMID: 40114965.

[3] Wu D, Tang Y, Li X, Xiong S, Zhang Z et al.. Characterization of protein lactylation in healthy and ischemic mouse hearts.. Front Cardiovasc Med 12:1644886. 2025. PMID: 41089239.