Search Results
Overview
| Uniprot ID | Q9CQ60 |
|---|---|
| Protein Name | 6-phosphogluconolactonase |
| Gene Name | Pgls |
| Organism | Mus musculus |
Kla Sites from experimental identification
| Position | Flanking peptide |
|---|---|
| 180 | APISDSPKPPPQRVT |
Function
Hydrolysis of 6-phosphogluconolactone to 6-phosphogluconate
Protein Sequence
10
MAAPAPSLIS
20
VFSSPQELGA
30
SLAQLVAQRA
40
ASCLEGDRGR
50
FALGLSGGSL
60
VSMLARDLPA
70
AAAPAGPASF
80
ARWTLGFCDE
90
RLVPFDHAES
100
TYGLYRTHLL
110
SKLPIPDSQV
120
LTINPALPVE
130
DAAEDYARKL
140
RQALQGDAVP
150
VFDLLILGVG
160
PDGHTCSLFP
170
DHPLLQEREK
180
IVAPISDSPK
190
PPPQRVTLTL
200
PVLNAAQSII
210
FVATGEGKAA
220
VLKRILEDKE
230
GTLPAALVQP
240
RTGALCWFLD
250
EAAARLLSVP
FEKHSTL
Gene Ontology
| Classification | GO ID | Description |
|---|---|---|
| Cellular Component | GO:0005829 | cytosol |
| Cellular Component | GO:0005654 | nucleoplasm |
| Molecular Function | GO:0017057 | 6-phosphogluconolactonase activity |
| Molecular Function | GO:0048029 | monosaccharide binding |
| Biological Process | GO:0005975 | carbohydrate metabolic process |
| Biological Process | GO:0006098 | pentose-phosphate shunt |
| Biological Process | GO:0009051 | pentose-phosphate shunt, oxidative branch |
Reference
[1] Chang J, Wu W, Qian P, Lu Z, He X et al.. Multi-omics study on the effect of moderate-intensity exercise on protein lactylation in mouse muscle tissue.. Front Cell Dev Biol 12:1472338. 2024. PMID: 39935788.
[2] Wu D, Tang Y, Li X, Xiong S, Zhang Z et al.. Characterization of protein lactylation in healthy and ischemic mouse hearts.. Front Cardiovasc Med 12:1644886. 2025. PMID: 41089239.