Search Results

Overview

Uniprot IDQ9CQZ6
Protein NameNADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 3
Gene NameNdufb3
OrganismMus musculus

Kla Sites from experimental identification

Position Flanking peptide
29 LPDYRQWKIEGTPLE
40 TPLETVQKKLAARGL

Function

Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that is believed not to be involved in catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone

Protein Sequence

10 MAAGHGHEHG 20 HEHGHGHGKM 30 ELPDYRQWKI 40 EGTPLETVQK 50 KLAARGLRDP 60 WARNEAWRYM 70 GGFAGNITFP 80 SVILKGFKWG 90 FAAFVVALGA 100 EYFLDSQNGD KKHH

Gene Ontology

Classification GO ID Description
Cellular Component GO:0005743 mitochondrial inner membrane
Cellular Component GO:0005739 mitochondrion
Cellular Component GO:0045271 respiratory chain complex I
Biological Process GO:0009060 aerobic respiration
Biological Process GO:0042776 proton motive force-driven mitochondrial ATP synthesis
Biological Process GO:0022904 respiratory electron transport chain

Reference

[1] Zhuo W, Zhang M, Tan J, Gao Y, Wang Y et al.. Lysine lactylation analysis of proteins in the heart of the Kawasaki disease mouse model.. Front Cell Dev Biol 13:1550220. 2025. PMID: 40114965.

[2] Wu D, Tang Y, Li X, Xiong S, Zhang Z et al.. Characterization of protein lactylation in healthy and ischemic mouse hearts.. Front Cardiovasc Med 12:1644886. 2025. PMID: 41089239.