Search Results
Overview
| Uniprot ID | Q9CRB6 |
|---|---|
| Protein Name | Tubulin polymerization-promoting protein family member 3 |
| Gene Name | Tppp3 |
| Organism | Mus musculus |
Kla Sites from experimental identification
| Position | Flanking peptide |
|---|---|
| 130 | DRLTDTSKYTGSHKE |
Function
Regulator of microtubule dynamic that has microtubule bundling activity (By similarity). Required for embryo implantation; possibly by regulating beta-catenin (PubMed:29901777). Also required for decidualization via regulation of beta-catenin (PubMed:30667362)
Protein Sequence
10
MAASTDIAGL
20
EESFRKFAIH
30
GDPKASGQEM
40
NGKNWAKLCK
50
DCKVADGKAV
60
TGTDVDIVFS
70
KVKAKSARVI
80
NYEEFKKALE
90
ELATKRFKGK
100
SKEEAFDAIC
110
QLIAGKEPAN
120
IGVTKAKTGG
130
AVDRLTDTSK
140
YTGSHKERFD
150
ESGKGKGIAG
160
RQDILDDSGY
170
VSAYKNAGTY
DAKVKK
Gene Ontology
| Classification | GO ID | Description |
|---|---|---|
| Cellular Component | GO:0005874 | microtubule |
| Cellular Component | GO:0097427 | microtubule bundle |
| Cellular Component | GO:0048471 | perinuclear region of cytoplasm |
| Molecular Function | GO:0015631 | tubulin binding |
| Biological Process | GO:0046697 | decidualization |
| Biological Process | GO:0007566 | embryo implantation |
| Biological Process | GO:0001578 | microtubule bundle formation |
| Biological Process | GO:0046785 | microtubule polymerization |
| Biological Process | GO:0032273 | positive regulation of protein polymerization |
Reference
[1] Wu D, Tang Y, Li X, Xiong S, Zhang Z et al.. Characterization of protein lactylation in healthy and ischemic mouse hearts.. Front Cardiovasc Med 12:1644886. 2025. PMID: 41089239.