Search Results
Overview
| Uniprot ID | Q9CX86 |
|---|---|
| Protein Name | Heterogeneous nuclear ribonucleoprotein A0 |
| Gene Name | Hnrnpa0 |
| Organism | Mus musculus |
Kla Sites from experimental identification
| Position | Flanking peptide |
|---|---|
| 159 | ADKAAVVKFHPIQGH |
Function
mRNA-binding component of ribonucleosomes. Specifically binds AU-rich element (ARE)-containing mRNAs. Involved in post-transcriptional regulation of cytokines mRNAs
Protein Sequence
10
MENSQLCKLF
20
IGGLNVQTSE
30
SGLRGHFEAF
40
GTLTDCVVVV
50
NPQTKRSRCF
60
GFVTYSNVEE
70
ADAAMAASPH
80
AVDGNTVELK
90
RAVSREDSAR
100
PGAHAKVKKL
110
FVGGLKGDVA
120
EGDLIEHFSQ
130
FGAVEKAEII
140
ADKQSGKKRG
150
FGFVYFQSHD
160
AADKAAVVKF
170
HPIQGHRVEV
180
KKAVPKEDIH
190
AGGGGARAAR
200
GGRGGGRGRG
210
GGGGGGGRDQ
220
NGLAKGGGGG
230
GGGYNSYGGY
240
GGYGAYGGGG
250
GGGGSYGGSD
260
YGNGFGGFGS
270
YSQHQSSYGP
280
MKSGGGGGGG
290
GSWGGRSNSG
300
PYRGGYGGGY
GGGSF
Gene Ontology
| Classification | GO ID | Description |
|---|---|---|
| Cellular Component | GO:0005654 | nucleoplasm |
| Cellular Component | GO:0005634 | nucleus |
| Cellular Component | GO:1990904 | ribonucleoprotein complex |
| Cellular Component | GO:0045202 | synapse |
| Molecular Function | GO:0035925 | mRNA 3'-UTR AU-rich region binding |
| Molecular Function | GO:0003729 | mRNA binding |
| Molecular Function | GO:0019901 | protein kinase binding |
| Biological Process | GO:0070935 | 3'-UTR-mediated mRNA stabilization |
| Biological Process | GO:0006954 | inflammatory response |
| Biological Process | GO:0032496 | response to lipopolysaccharide |
Reference
[1] Wu D, Tang Y, Li X, Xiong S, Zhang Z et al.. Characterization of protein lactylation in healthy and ischemic mouse hearts.. Front Cardiovasc Med 12:1644886. 2025. PMID: 41089239.