Search Results
Overview
| Uniprot ID | Q9CXZ1 |
|---|---|
| Protein Name | NADH dehydrogenase [ubiquinone] iron-sulfur protein 4, mitochondrial |
| Gene Name | Ndufs4 |
| Organism | Mus musculus |
Kla Sites from experimental identification
| Position | Flanking peptide |
|---|---|
| 150 | WSYDVEEKKVPKPKS |
| 95 | QSGVNNTKKWKMEFD |
| 98 | VNNTKKWKMEFDTRE |
Function
Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that is believed not to be involved in catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone
Protein Sequence
10
MAAVSISVSL
20
RQAMLGRRAM
30
ATAAVSVCRV
40
PSRLLSTSTW
50
KLADNQTRDT
60
QLITVDEKLD
70
ITTLTGVPEE
80
HIKTRKVRIF
90
VPARNNMQSG
100
VNNTKKWKME
110
FDTRERWENP
120
LMGWASTADP
130
LSNMVLTFSA
140
KEDAIAFAEK
150
NGWSYDVEEK
160
KVPKPKSKSY
170
GANFSWNKRT
RVSTK
Gene Ontology
| Classification | GO ID | Description |
|---|---|---|
| Cellular Component | GO:0005743 | mitochondrial inner membrane |
| Cellular Component | GO:0005739 | mitochondrion |
| Cellular Component | GO:0033011 | perinuclear theca |
| Cellular Component | GO:0045271 | respiratory chain complex I |
| Cellular Component | GO:0120238 | sperm glycocalyx |
| Molecular Function | GO:0008137 | NADH dehydrogenase (ubiquinone) activity |
| Biological Process | GO:0030534 | adult behavior |
| Biological Process | GO:0007628 | adult walking behavior |
| Biological Process | GO:0009060 | aerobic respiration |
| Biological Process | GO:0007420 | brain development |
| Biological Process | GO:0071453 | cellular response to oxygen levels |
| Biological Process | GO:0050890 | cognition |
| Biological Process | GO:0042417 | dopamine metabolic process |
| Biological Process | GO:0006954 | inflammatory response |
| Biological Process | GO:0045087 | innate immune response |
| Biological Process | GO:0032981 | mitochondrial respiratory chain complex I assembly |
| Biological Process | GO:0051402 | neuron apoptotic process |
| Biological Process | GO:0048666 | neuron development |
| Biological Process | GO:0006119 | oxidative phosphorylation |
| Biological Process | GO:0042776 | proton motive force-driven mitochondrial ATP synthesis |
| Biological Process | GO:0036343 | psychomotor behavior |
| Biological Process | GO:0072593 | reactive oxygen species metabolic process |
| Biological Process | GO:0051881 | regulation of mitochondrial membrane potential |
| Biological Process | GO:0001932 | regulation of protein phosphorylation |
| Biological Process | GO:0022904 | respiratory electron transport chain |
| Biological Process | GO:0003016 | respiratory system process |
| Biological Process | GO:0051591 | response to cAMP |
| Biological Process | GO:0014876 | response to injury involved in regulation of muscle adaptation |
| Biological Process | GO:0007605 | sensory perception of sound |
| Biological Process | GO:0007601 | visual perception |
Reference
[1] Zhuo W, Zhang M, Tan J, Gao Y, Wang Y et al.. Lysine lactylation analysis of proteins in the heart of the Kawasaki disease mouse model.. Front Cell Dev Biol 13:1550220. 2025. PMID: 40114965.
[2] Wu D, Tang Y, Li X, Xiong S, Zhang Z et al.. Characterization of protein lactylation in healthy and ischemic mouse hearts.. Front Cardiovasc Med 12:1644886. 2025. PMID: 41089239.