Search Results
Overview
| Uniprot ID | Q9CZR8 |
|---|---|
| Protein Name | Elongation factor Ts, mitochondrial |
| Gene Name | Tsfm |
| Organism | Mus musculus |
Kla Sites from experimental identification
| Position | Flanking peptide |
|---|---|
| 55 | LLMKLRRKTGYSFVN |
| 65 | YSFVNCKKALETCGG |
| 75 | ETCGGDLKQAEDWLH |
| 87 | WLHKQAQKEGWSKAA |
Function
Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF-Tu.GTP complex up to the GTP hydrolysis stage on the ribosome. Participates in mitochondrial translation (By similarity)
Protein Sequence
10
MSLLRSLRFF
20
PVACTGRSAR
30
AVLLQPSQPW
40
LTFHAGPSLS
50
SAASSKELLM
60
KLRRKTGYSF
70
VNCKKALETC
80
GGDLKQAEDW
90
LHKQAQKEGW
100
SKAAKLHGRK
110
TKEGLIGLLQ
120
EGNTAVLVEV
130
NCETDFVSRN
140
LKFQQLVQQV
150
ALGTMAHCQN
160
LTDRLSTYSK
170
GFLNSSELSE
180
LAAGPDREGS
190
LKDQLALAIG
200
KLGENMILKR
210
AAWVKVPSGF
220
YVGSYVHGVT
230
QSPSLQNLVL
240
GKYGALVICE
250
TPEQIANLEE
260
VGRRLGQHVV
270
GMAPLSVGSL
280
DDEPGGETET
290
RMLPQPYLLD
300
PSITLGQYVQ
310
PQGVTVVDFV
320
RFECGEDEQV
AEAE
Gene Ontology
| Classification | GO ID | Description |
|---|---|---|
| Biological Process | GO:0032543 | mitochondrial translation |
| Biological Process | GO:0070125 | mitochondrial translational elongation |
| Cellular Component | GO:0005759 | mitochondrial matrix |
| Cellular Component | GO:0005739 | mitochondrion |
| Cellular Component | GO:0005654 | nucleoplasm |
| Molecular Function | GO:0005085 | guanyl-nucleotide exchange factor activity |
| Molecular Function | GO:0003746 | translation elongation factor activity |
Reference
[1] Zhuo W, Zhang M, Tan J, Gao Y, Wang Y et al.. Lysine lactylation analysis of proteins in the heart of the Kawasaki disease mouse model.. Front Cell Dev Biol 13:1550220. 2025. PMID: 40114965.
[2] Wu D, Tang Y, Li X, Xiong S, Zhang Z et al.. Characterization of protein lactylation in healthy and ischemic mouse hearts.. Front Cardiovasc Med 12:1644886. 2025. PMID: 41089239.