Search Results
Overview
| Uniprot ID | Q9D404 |
|---|---|
| Protein Name | 3-oxoacyl-[acyl-carrier-protein] synthase, mitochondrial |
| Gene Name | Oxsm |
| Organism | Mus musculus |
Kla Sites from experimental identification
| Position | Flanking peptide |
|---|---|
| 138 | KDSGWHPKREADQVA |
Function
May play a role in the biosynthesis of lipoic acid as well as longer chain fatty acids required for optimal mitochondrial function
Protein Sequence
10
MLSKCLQHFL
20
KATISHPYPA
30
SYSWLISKHR
40
FYGTVPAAML
50
RRRVVITGIG
60
LVTPLGVGTQ
70
LVWDRLLRGE
80
SGIVSVVGDE
90
YKNIPCSVAA
100
YVPRGPHEGQ
110
FNEENFVSKS
120
DAKSMSSSTI
130
MAVGAAELAL
140
KDSGWHPKRE
150
ADQVATGVAI
160
GMGMVPLEVI
170
SETALLFQTK
180
GYNKVSPFFV
190
PKILINMAAG
200
QVSIRYKLKG
210
PNHSVSTACT
220
TGAHAVGDSF
230
RFIAHGDADV
240
MVAGGTDSCI
250
SPLSLAGFSR
260
ARALSSNPDP
270
KLACRPFHPE
280
RDGFVMGEGA
290
AVLVLEEHEH
300
AVQRGARIYA
310
EILGYGLSGD
320
AGHITAPDPE
330
GEGALRCMAA
340
AVKDAGVSPE
350
QISYVNAHAT
360
STPLGDAAEN
370
RAIKRLFRDH
380
ACALAISSTK
390
GATGHLLGAA
400
GAVEATFTAL
410
ACYHQKLPPT
420
LNLDCTEPEF
430
DLNYVPLESQ
440
EWKAEGRCIG
450
LTNSFGFGGT
NATLCIAGM
Gene Ontology
| Classification | GO ID | Description |
|---|---|---|
| Cellular Component | GO:0005829 | cytosol |
| Cellular Component | GO:0005739 | mitochondrion |
| Molecular Function | GO:0004315 | 3-oxoacyl-[acyl-carrier-protein] synthase activity |
| Biological Process | GO:0006637 | acyl-CoA metabolic process |
| Biological Process | GO:0006633 | fatty acid biosynthetic process |
| Biological Process | GO:0051792 | medium-chain fatty acid biosynthetic process |
| Biological Process | GO:0051790 | short-chain fatty acid biosynthetic process |
Reference
[1] Zhuo W, Zhang M, Tan J, Gao Y, Wang Y et al.. Lysine lactylation analysis of proteins in the heart of the Kawasaki disease mouse model.. Front Cell Dev Biol 13:1550220. 2025. PMID: 40114965.
[2] Wu D, Tang Y, Li X, Xiong S, Zhang Z et al.. Characterization of protein lactylation in healthy and ischemic mouse hearts.. Front Cardiovasc Med 12:1644886. 2025. PMID: 41089239.