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Overview

Uniprot IDQ9D4K4
Protein NameFANCD2 opposite strand protein
Gene NameFancd2os
OrganismMus musculus

Kla Sites from experimental identification

Position Flanking peptide
168 LLLYATYKKCTFALQ

Function

Reduces testosterone levels by inhibiting steroidogenic enzymes and by promoting apoptosis in Leydig cells

Protein Sequence

10 MAGYQLWSPW 20 TPLDESFQWL 30 RHTTPTPSSK 40 HPFRASPCFP 50 HTPSDLEVQL 60 CLQEVTLVLD 70 RPLVEPGESP 80 KLPCHTSELR 90 AVSNKKGVVR 100 KPQPVRLSGV 110 DSVFGRVITA 120 QPPKWTGTFR 130 VSDKSAFCKI 140 ISREHQWPTG 150 LKEPQVQMTV 160 TMCKQMLRSI 170 LLLYATYKKC TFALQHSK

Gene Ontology

Classification GO ID Description
Cellular Component GO:0005737 cytoplasm
Biological Process GO:2000225 negative regulation of testosterone biosynthetic process

Reference

[1] Zhuo W, Zhang M, Tan J, Gao Y, Wang Y et al.. Lysine lactylation analysis of proteins in the heart of the Kawasaki disease mouse model.. Front Cell Dev Biol 13:1550220. 2025. PMID: 40114965.