Search Results

Overview

Uniprot ID	Q9DC69
Protein Name	NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 9, mitochondrial
Gene Name	Ndufa9
Organism	Mus musculus

Kla Sites from experimental identification

Position	Flanking peptide
157	RAIAQASKEAGVERF
175	SHLNASMKSSSKSLR
189	RSKAVGEKEVRSVFP
237	SLGFKTVKQPVYVAD
370	SSEIEETKPAKTVNY

Function

Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that is believed not to be involved in catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone

Protein Sequence

10 MAAAVRFRVV 20 RALPMSRPAI 30 TAAATSVFCG 40 SSHRQLHHAV 50 IPHGKGGRSS 60 VSGVVATVFG 70 ATGFLGRYVV 80 NHLGRMGSQV 90 IIPYRCDVYD 100 IMHLRLMGDL 110 GQLTFLEWDA 120 RDKDSIRKAV 130 QHSNVVINLI 140 GREWETRNFD 150 FEDVFVNIPR 160 AIAQASKEAG 170 VERFIHVSHL 180 NASMKSSSKS 190 LRSKAVGEKE 200 VRSVFPEAII 210 IRPSDIFGRE 220 DRFLNHFANY 230 RWFLAVPLVS 240 LGFKTVKQPV 250 YVADVSKGIV 260 NATKDPDAVG 270 KTFAFTGPNR 280 YLLFHLVKYI 290 FGMTHRTFIP 300 YPLPLFVYSW 310 IGKLFGLSPF 320 EPWTTKDKVE 330 RIHISDVMPT 340 DLPGLEDLGV 350 QPTPLELKSI 360 EVLRRHRTYR 370 WLSSEIEETK PAKTVNY

Gene Ontology

Classification	GO ID	Description
Cellular Component	GO:0005743	mitochondrial inner membrane
Cellular Component	GO:0005759	mitochondrial matrix
Cellular Component	GO:0031966	mitochondrial membrane
Cellular Component	GO:0005739	mitochondrion
Cellular Component	GO:0045271	respiratory chain complex I
Molecular Function	GO:0003954	NADH dehydrogenase activity
Molecular Function	GO:0044877	protein-containing complex binding
Biological Process	GO:0009060	aerobic respiration
Biological Process	GO:0007623	circadian rhythm
Biological Process	GO:0042776	proton motive force-driven mitochondrial ATP synthesis
Biological Process	GO:0022904	respiratory electron transport chain
Biological Process	GO:0006744	ubiquinone biosynthetic process

Reference

[1] Chang J, Wu W, Qian P, Lu Z, He X et al.. Multi-omics study on the effect of moderate-intensity exercise on protein lactylation in mouse muscle tissue.. Front Cell Dev Biol 12:1472338. 2024. PMID: 39935788.

[2] Zhuo W, Zhang M, Tan J, Gao Y, Wang Y et al.. Lysine lactylation analysis of proteins in the heart of the Kawasaki disease mouse model.. Front Cell Dev Biol 13:1550220. 2025. PMID: 40114965.

[3] Wu D, Tang Y, Li X, Xiong S, Zhang Z et al.. Characterization of protein lactylation in healthy and ischemic mouse hearts.. Front Cardiovasc Med 12:1644886. 2025. PMID: 41089239.