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Overview

Uniprot IDQ9DCJ5
Protein NameNADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 8
Gene NameNdufa8
OrganismMus musculus

Kla Sites from experimental identification

Position Flanking peptide
41 AQCDKTNKEFMLCRW

Function

Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that is believed not to be involved in catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone

Protein Sequence

10 MPGIVELPTL 20 EELKVEEVKV 30 SSAVLKAAAH 40 HYGAQCDKTN 50 KEFMLCRWEE 60 KDPRRCLKEG 70 KLVNGCALNF 80 FRQIKSHCAE 90 PFTEYWTCLD 100 YSNMQLFRHC 110 RQQQAKFDQC 120 VLDKLGWVRP 130 DLGQLSKVTK 140 VKTDRPLPEN 150 PYHSRARPEP 160 NPVIEGDLKP 170 AKHGTRFFFW TV

Gene Ontology

Classification GO ID Description
Cellular Component GO:0005743 mitochondrial inner membrane
Cellular Component GO:0005758 mitochondrial intermembrane space
Cellular Component GO:0005739 mitochondrion
Cellular Component GO:0045271 respiratory chain complex I
Molecular Function GO:0044877 protein-containing complex binding
Biological Process GO:0009060 aerobic respiration
Biological Process GO:0006120 mitochondrial electron transport, NADH to ubiquinone
Biological Process GO:0042776 proton motive force-driven mitochondrial ATP synthesis

Reference

[1] Zhuo W, Zhang M, Tan J, Gao Y, Wang Y et al.. Lysine lactylation analysis of proteins in the heart of the Kawasaki disease mouse model.. Front Cell Dev Biol 13:1550220. 2025. PMID: 40114965.