Search Results
Overview
| Uniprot ID | Q9H061 |
|---|---|
| Protein Name | Transmembrane protein 126A |
| Gene Name | TMEM126A |
| Organism | Homo sapiens |
Kla Sites from experimental identification
| Position | Flanking peptide |
|---|---|
| 5 | ***MENHKSNNKENI |
Function
Protein required for the cotranslational protein quality control in the inner membrane of the mitochondria (PubMed:38199007). Associates with newly synthesized polypeptides and may act as a chaperone that cooperates with OXA1L for the insertion of newly synthesized mitochondrial proteins into the inner membrane (PubMed:38199007). Required for the assembly of the ND4 module of mitochondrial complex I (PubMed:33879611, PubMed:33882309)
Protein Sequence
10
MENHKSNNKE
20
NITIVDISRK
30
INQLPEAERN
40
LLENGSVYVG
50
LNAALCGLIA
60
NSLFRRILNV
70
TKARIAAGLP
80
MAGIPFLTTD
90
LTYRCFVSFP
100
LNTGDLDCET
110
CTITRSGLTG
120
LVIGGLYPVF
130
LAIPVNGGLA
140
ARYQSALLPH
150
KGNILSYWIR
160
TSKPVFRKML
170
FPILLQTMFS
180
AYLGSEQYKL
190
LIKALQLSEP
GKEIH
Gene Ontology
| Classification | GO ID | Description |
|---|---|---|
| Cellular Component | GO:0005743 | mitochondrial inner membrane |
| Cellular Component | GO:0005739 | mitochondrion |
| Cellular Component | GO:0005886 | plasma membrane |
| Biological Process | GO:0141164 | mitochondrial protein quality control |
| Biological Process | GO:0032981 | mitochondrial respiratory chain complex I assembly |
| Biological Process | GO:0021554 | optic nerve development |
| Biological Process | GO:0032979 | protein insertion into mitochondrial inner membrane from matrix |
Reference
PMID: N/A