Search Results
Overview
| Uniprot ID | Q9H089 |
|---|---|
| Protein Name | Large subunit GTPase 1 homolog |
| Gene Name | LSG1 |
| Organism | Homo sapiens |
Kla Sites from experimental identification
| Position | Flanking peptide |
|---|---|
| 81 | VAEKLNIKFVPAEAR |
Function
Functions as a GTPase (PubMed:16209721). May act by mediating the release of NMD3 from the 60S ribosomal subunit after export into the cytoplasm during the 60S ribosomal subunit maturation (PubMed:31148378)
Protein Sequence
10
MGRRRAPAGG
20
SLGRALMRHQ
30
TQRSRSHRHT
40
DSWLHTSELN
50
DGYDWGRLNL
60
QSVTEQSSLD
70
DFLATAELAG
80
TEFVAEKLNI
90
KFVPAEARTG
100
LLSFEESQRI
110
KKLHEENKQF
120
LCIPRRPNWN
130
QNTTPEELKQ
140
AEKDNFLEWR
150
RQLVRLEEEQ
160
KLILTPFERN
170
LDFWRQLWRV
180
IERSDIVVQI
190
VDARNPLLFR
200
CEDLECYVKE
210
MDANKENVIL
220
INKADLLTAE
230
QRSAWAMYFE
240
KEDVKVIFWS
250
ALAGAIPLNG
260
DSEEEANRDD
270
RQSNTTKFGH
280
SSFDQAEISH
290
SESEHLPARD
300
SPSLSENPTT
310
DEDDSEYEDC
320
PEEEEDDWQT
330
CSEEDGPKEE
340
DCSQDWKESS
350
TADSEARSRK
360
TPQKRQIHNF
370
SHLVSKQELL
380
ELFKELHTGR
390
KVKDGQLTVG
400
LVGYPNVGKS
410
STINTIMGNK
420
KVSVSATPGH
430
TKHFQTLYVE
440
PGLCLCDCPG
450
LVMPSFVSTK
460
AEMTCSGILP
470
IDQMRDHVPP
480
VSLVCQNIPR
490
HVLEATYGIN
500
IITPREDEDP
510
HRPPTSEELL
520
TAYGYMRGFM
530
TAHGQPDQPR
540
SARYILKDYV
550
SGKLLYCHPP
560
PGRDPVTFQH
570
QHQRLLENKM
580
NSDEIKMQLG
590
RNKKAKQIEN
600
IVDKTFFHQE
610
NVRALTKGVQ
620
AVMGYKPGSG
630
VVTASTASSE
640
NGAGKPWKKH
650
GNRNKKEKSR
RLYKHLDM
Gene Ontology
| Classification | GO ID | Description |
|---|---|---|
| Cellular Component | GO:0015030 | Cajal body |
| Cellular Component | GO:0005829 | cytosol |
| Cellular Component | GO:0005783 | endoplasmic reticulum |
| Cellular Component | GO:0016020 | membrane |
| Cellular Component | GO:0016604 | nuclear body |
| Cellular Component | GO:0005654 | nucleoplasm |
| Molecular Function | GO:0005525 | GTP binding |
| Molecular Function | GO:0003924 | GTPase activity |
| Biological Process | GO:0051168 | nuclear export |
| Biological Process | GO:0015031 | protein transport |
| Biological Process | GO:0000054 | ribosomal subunit export from nucleus |
Reference
[1] Wu Q, Li Z, Gong T, Zheng X, Zhou X et al.. Porphyromonas gingivalis infection induces lysine lactylation reprogramming in human umbilical vein endothelial cells.. Front Cell Infect Microbiol 16:1706727. 2026. PMID: 41696360.