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Overview

Uniprot IDQ9H115
Protein NameBeta-soluble NSF attachment protein
Gene NameNAPB
OrganismHomo sapiens

Kla Sites from experimental identification

Position Flanking peptide
203 PLLKYSAKDYFFKAA
93 VDAGNAYKKADPQEA

Function

Required for vesicular transport between the endoplasmic reticulum and the Golgi apparatus

Protein Sequence

10 MDNAGKEREA 20 VQLMAEAEKR 30 VKASHSFLRG 40 LFGGNTRIEE 50 ACEMYTRAAN 60 MFKMAKNWSA 70 AGNAFCQAAK 80 LHMQLQSKHD 90 SATSFVDAGN 100 AYKKADPQEA 110 INCLNAAIDI 120 YTDMGRFTIA 130 AKHHITIAEI 140 YETELVDIEK 150 AIAHYEQSAD 160 YYKGEESNSS 170 ANKCLLKVAA 180 YAAQLEQYQK 190 AIEIYEQVGA 200 NTMDNPLLKY 210 SAKDYFFKAA 220 LCHFIVDELN 230 AKLALEKYEE 240 MFPAFTDSRE 250 CKLLKKLLEA 260 HEEQNSEAYT 270 EAVKEFDSIS 280 RLDQWLTTML 290 LRIKKSIQGD GEGDGDLK

Gene Ontology

Classification GO ID Description
Cellular Component GO:0070062 extracellular exosome
Cellular Component GO:0098978 glutamatergic synapse
Cellular Component GO:0070044 synaptobrevin 2-SNAP-25-syntaxin-1a complex
Cellular Component GO:0043195 terminal bouton
Molecular Function GO:0005483 soluble NSF attachment protein activity
Molecular Function GO:0019905 syntaxin binding
Biological Process GO:0006886 intracellular protein transport
Biological Process GO:0010807 regulation of synaptic vesicle priming
Biological Process GO:0035494 SNARE complex disassembly
Biological Process GO:0035249 synaptic transmission, glutamatergic

Reference

[1] Shi CM, Wang QC, Li XL, Yang YH, Tang XY et al.. Global Profiling of Protein Lactylation in Human Hippocampi.. Proteomics Clin Appl 19(2):e202400061. 2025 Mar. PMID: 39610256.