Search Results
Overview
| Uniprot ID | Q9H190 |
|---|---|
| Protein Name | Syntenin-2 |
| Gene Name | SDCBP2 |
| Organism | Homo sapiens |
Kla Sites from experimental identification
| Position | Flanking peptide |
|---|---|
| 217 | GKIVSLVKGSSAARN |
Function
Binds phosphatidylinositol 4,5-bisphosphate (PIP2). May play a role in the organization of nuclear PIP2, cell division and cell survival (PubMed:15961997)
Protein Sequence
10
MSSLYPSLED
20
LKVDQAIQAQ
30
VRASPKMPAL
40
PVQATAISPP
50
PVLYPNLAEL
60
ENYMGLSLSS
70
QEVQESLLQI
80
PEGDSTAVSG
90
PGPGQMVAPV
100
TGYSLGVRRA
110
EIKPGVREIH
120
LCKDERGKTG
130
LRLRKVDQGL
140
FVQLVQANTP
150
ASLVGLRFGD
160
QLLQIDGRDC
170
AGWSSHKAHQ
180
VVKKASGDKI
190
VVVVRDRPFQ
200
RTVTMHKDSM
210
GHVGFVIKKG
220
KIVSLVKGSS
230
AARNGLLTNH
240
YVCEVDGQNV
250
IGLKDKKIME
260
ILATAGNVVT
270
LTIIPSVIYE
280
HMVKKLPPVL
290
LHHTMDHSIP
DA
Gene Ontology
| Classification | GO ID | Description |
|---|---|---|
| Cellular Component | GO:0005737 | cytoplasm |
| Cellular Component | GO:0005829 | cytosol |
| Cellular Component | GO:0070062 | extracellular exosome |
| Cellular Component | GO:0016607 | nuclear speck |
| Cellular Component | GO:0005730 | nucleolus |
| Cellular Component | GO:0005654 | nucleoplasm |
| Cellular Component | GO:0005886 | plasma membrane |
| Molecular Function | GO:0042802 | identical protein binding |
| Molecular Function | GO:0005546 | phosphatidylinositol-4,5-bisphosphate binding |
| Molecular Function | GO:0046982 | protein heterodimerization activity |
| Molecular Function | GO:0042803 | protein homodimerization activity |
| Biological Process | GO:0008283 | cell population proliferation |
| Biological Process | GO:0035556 | intracellular signal transduction |
| Biological Process | GO:0046907 | intracellular transport |
| Biological Process | GO:0007399 | nervous system development |
Reference
[1] Yang Z, Yan C, Ma J, Peng P, Ren X et al.. Lactylome analysis suggests lactylation-dependent mechanisms of metabolic adaptation in hepatocellular carcinoma.. Nat Metab 5(1):61-79. 2023 Jan. PMID: 36593272.