Search Results
Overview
| Uniprot ID | Q9H410 |
|---|---|
| Protein Name | Kinetochore-associated protein DSN1 homolog |
| Gene Name | DSN1 |
| Organism | Homo sapiens |
Kla Sites from experimental identification
| Position | Flanking peptide |
|---|---|
| 338 | SPARKLLKLQLQNPP |
Function
Part of the MIS12 complex which is required for normal chromosome alignment and segregation and kinetochore formation during mitosis
Protein Sequence
10
MTSVTRSEII
20
DEKGPVMSKT
30
HDHQLESSLS
40
PVEVFAKTSA
50
SLEMNQGVSE
60
ERIHLGSSPK
70
KGGNCDLSHQ
80
ERLQSKSLHL
90
SPQEQSASYQ
100
DRRQSWRRAS
110
MKETNRRKSL
120
HPIHQGITEL
130
SRSISVDLAE
140
SKRLGCLLLS
150
SFQFSIQKLE
160
PFLRDTKGFS
170
LESFRAKASS
180
LSEELKHFAD
190
GLETDGTLQK
200
CFEDSNGKAS
210
DFSLEASVAE
220
MKEYITKFSL
230
ERQTWDQLLL
240
HYQQEAKEIL
250
SRGSTEAKIT
260
EVKVEPMTYL
270
GSSQNEVLNT
280
KPDYQKILQN
290
QSKVFDCMEL
300
VMDELQGSVK
310
QLQAFMDEST
320
QCFQKVSVQL
330
GKRSMQQLDP
340
SPARKLLKLQ
350
LQNPPAIHGS
GSGSCQ
Gene Ontology
| Classification | GO ID | Description |
|---|---|---|
| Cellular Component | GO:0035578 | azurophil granule lumen |
| Cellular Component | GO:0005829 | cytosol |
| Cellular Component | GO:0005576 | extracellular region |
| Cellular Component | GO:0001650 | fibrillar center |
| Cellular Component | GO:0000776 | kinetochore |
| Cellular Component | GO:0000444 | MIS12/MIND type complex |
| Cellular Component | GO:0016604 | nuclear body |
| Cellular Component | GO:0005654 | nucleoplasm |
| Cellular Component | GO:0005634 | nucleus |
| Cellular Component | GO:0000940 | outer kinetochore |
| Cellular Component | GO:0000922 | spindle pole |
| Biological Process | GO:0008608 | attachment of spindle microtubules to kinetochore |
| Biological Process | GO:0051301 | cell division |
Reference
[1] Yang D, Yin J, Shan L, Yi X, Zhang W et al.. Identification of lysine-lactylated substrates in gastric cancer cells.. iScience 25(7):104630. 2022 Jul 15. PMID: 35800753.