Search Results

Overview

Uniprot IDQ9H582
Protein NameZinc finger protein 644
Gene NameZNF644
OrganismHomo sapiens

Kla Sites from experimental identification

Position Flanking peptide
1023 TGTGTPVKRVRKAIE
1192 NSAISPQKIHNQTAR
1205 ARKRFVQKCVLPLNE
1234 MHSALDCKQKKSRSR
127 VSHSSLTKTSNMNKG
317 DSNCVPNKSKMQEVD
344 SQKYALSKVKPESTD
573 TQKKTFMKDSVVGSS
589 KSATYICKMCPFTTS
645 DSTKTLTKQQSTTFP
653 QQSTTFPKNSALKQD
658 FPKNSALKQDVKRTF
676 SQSSSFSKIHKRPHR
679 SSFSKIHKRPHRIQK
720 SSVDQKPKYFHQAAK
733 AKEKSNAKANSHYLY
801 AKRPESFKDHRRVAV
843 MTVVVLQKLNSAEKK

Function

May be involved in transcriptional regulation

Protein Sequence

10 MRSFLQQDVN 20 KTKSRLNVLN 30 GLANNMDDLK 40 INTDITGAKE 50 ELLDDNNFIS 60 DKESGVHKPK 70 DCQTSFQKNN 80 TLTLPEELSK 90 DKSENALSGG 100 QSSLFIHAGA 110 PTVSSENFIL 120 PKGAAVNGPV 130 SHSSLTKTSN 140 MNKGSVSLTT 150 GQPVDQPTTE 160 SCSTLKVAAD 170 LQLSTPQKAS 180 QHQVLFLLSD 190 VAHAKNPTHS 200 NKKLPTSASV 210 GCDIQNSVGS 220 NIKSDGTLIN 230 QVEVGEDGED 240 LLVKDDCVNT 250 VTGISSGTDG 260 FRSENDTNWD 270 PQKEFIQFLM 280 TNEETVDKAP 290 PHSKIGLEKK 300 RKRKMDVSKI 310 TRYTEDCFSD 320 SNCVPNKSKM 330 QEVDFLEQNE 340 ELQAVDSQKY 350 ALSKVKPEST 360 DEDLESVDAF 370 QHLIYNPDKC 380 GEESSPVHTS 390 TFLSNTLKKK 400 CEESDSESPA 410 TFSTEEPSFY 420 PCTKCNVNFR 430 EKKHLHRHMM 440 YHLDGNSHFR 450 HLNVPRPYAC 460 RECGRTFRDR 470 NSLLKHMIIH 480 QERRQKLMEE 490 IRELKELQDE 500 GRSARLQCPQ 510 CVFGTNCPKT 520 FVQHAKTHEK 530 DKRYYCCEEC 540 NFMAVTENEL 550 ECHRGIAHGA 560 VVKCPMVTSD 570 IAQRKTQKKT 580 FMKDSVVGSS 590 KKSATYICKM 600 CPFTTSAKSV 610 LKKHTEYLHS 620 SSCVDSFGSP 630 LGLDKRKNDI 640 LEEPVDSDST 650 KTLTKQQSTT 660 FPKNSALKQD 670 VKRTFGSTSQ 680 SSSFSKIHKR 690 PHRIQKARKS 700 IAQSGVNMCN 710 QNSSPHKNVT 720 IKSSVDQKPK 730 YFHQAAKEKS 740 NAKANSHYLY 750 RHKYENYRMI 760 KKSGESYPVH 770 FKKEEASSLN 780 SLHLFSSSSN 790 SHNNFISDPH 800 KPDAKRPESF 810 KDHRRVAVKR 820 VIKESKKESS 830 VGGEDLDSYP 840 DFLHKMTVVV 850 LQKLNSAEKK 860 DSYETEDESS 870 WDNVELGDYT 880 TQAIEDETYS 890 DINQEHVNLF 900 PLFKSKVEGQ 910 EPGENATLSY 920 DQNDGFYFEY 930 YEDTGSNNFL 940 HEIHDPQHLE 950 TADASLSKHS 960 SVFHWTDLSL 970 EKKSCPYCPA 980 TFETGVGLSN 990 HVRGHLHRAG 1000 LSYEARHVVS 1010 PEQIATSDKM 1020 QHFKRTGTGT 1030 PVKRVRKAIE 1040 KSETTSEHTC 1050 QLCGGWFDTK 1060 IGLSNHVRGH 1070 LKRLGKTKWD 1080 AHKSPICVLN 1090 EMMQNEEKYE 1100 KILKALNSRR 1110 IIPRPFVAQK 1120 LASSDDFISQ 1130 NVIPLEAYRN 1140 GLKTEALSVS 1150 ASEEEGLNFL 1160 NEYDETKPEL 1170 PSGKKNQSLT 1180 LIELLKNKRM 1190 GEERNSAISP 1200 QKIHNQTARK 1210 RFVQKCVLPL 1220 NEDSPLMYQP 1230 QKMDLTMHSA 1240 LDCKQKKSRS 1250 RSGSKKKMLT 1260 LPHGADEVYI 1270 LRCRFCGLVF 1280 RGPLSVQEDW 1290 IKHLQRHIVN 1300 ANLPRTGAGM 1310 VEVTSLLKKP 1320 ASITETSFSL LMAEAAS

Gene Ontology

Classification GO ID Description
Cellular Component GO:0005634 nucleus
Molecular Function GO:0000981 DNA-binding transcription factor activity, RNA polymerase II-specific
Molecular Function GO:0000978 RNA polymerase II cis-regulatory region sequence-specific DNA binding
Molecular Function GO:0001222 transcription corepressor binding
Molecular Function GO:0008270 zinc ion binding
Biological Process GO:0006351 DNA-templated transcription
Biological Process GO:0006357 regulation of transcription by RNA polymerase II

Reference

[1] He C, Zhang J, Bai X, Lu C, Zhang K. Lysine lactylation-based insight to understanding the characterization of cervical cancer.. Biochim Biophys Acta Mol Basis Dis 1870(7):167356. 2024 Oct. PMID: 39025375.

[2] Wu Q, Li Z, Gong T, Zheng X, Zhou X et al.. Porphyromonas gingivalis infection induces lysine lactylation reprogramming in human umbilical vein endothelial cells.. Front Cell Infect Microbiol 16:1706727. 2026. PMID: 41696360.