Search Results
Overview
| Uniprot ID | Q9H7S9 |
|---|---|
| Protein Name | Zinc finger protein 703 |
| Gene Name | ZNF703 |
| Organism | Homo sapiens |
Kla Sites from experimental identification
| Position | Flanking peptide |
|---|---|
| 141 | ASAAAALKQLGDSPA |
| 159 | SSFKPYSKGSGGGDS |
Function
Transcriptional corepressor which does not bind directly to DNA and may regulate transcription through recruitment of histone deacetylases to gene promoters. Regulates cell adhesion, migration and proliferation. May be required for segmental gene expression during hindbrain development
Protein Sequence
10
MSDSPAGSNP
20
RTPESSGSGS
30
GGGGKRPAVP
40
AAVSLLPPAD
50
PLRQANRLPI
60
RVLKMLSAHT
70
GHLLHPEYLQ
80
PLSSTPVSPI
90
ELDAKKSPLA
100
LLAQTCSQIG
110
KPDPPPSSKL
120
NSVAAAANGL
130
GAEKDPGRSA
140
PGAASAAAAL
150
KQLGDSPAED
160
KSSFKPYSKG
170
SGGGDSRKDS
180
GSSSVSSTSS
190
SSSSSPGDKA
200
GFRVPSAACP
210
PFPPHGAPVS
220
ASSSSSSPGG
230
SRGGSPHHSD
240
CKNGGGVGGG
250
ELDKKDQEPK
260
PSPEPAAVSR
270
GGGGEPGAHG
280
GAESGASGRK
290
SEPPSALVGA
300
GHVAPVSPYK
310
PGHSVFPLPP
320
SSIGYHGSIV
330
GAYAGYPSQF
340
VPGLDPSKSG
350
LVGGQLSGGL
360
GLPPGKPPSS
370
SPLTGASPPS
380
FLQGLCRDPY
390
CLGGYHGASH
400
LGGSSCSTCS
410
AHDPAGPSLK
420
AGGYPLVYPG
430
HPLQPAALSS
440
SAAQAALPGH
450
PLYTYGFMLQ
460
NEPLPHSCNW
470
VAASGPCDKR
480
FATSEELLSH
490
LRTHTALPGA
500
EKLLAAYPGA
510
SGLGSAAAAA
520
AAAASCHLHL
530
PPPAAPGSPG
540
SLSLRNPHTL
550
GLSRYHPYGK
560
SHLSTAGGLA
570
VPSLPTAGPY
580
YSPYALYGQR
590
LASASALGYQ
Gene Ontology
| Classification | GO ID | Description |
|---|---|---|
| Cellular Component | GO:0005737 | cytoplasm |
| Cellular Component | GO:0005739 | mitochondrion |
| Cellular Component | GO:0016363 | nuclear matrix |
| Cellular Component | GO:0005634 | nucleus |
| Cellular Component | GO:0032991 | protein-containing complex |
| Molecular Function | GO:0140297 | DNA-binding transcription factor binding |
| Molecular Function | GO:0008270 | zinc ion binding |
| Biological Process | GO:0034333 | adherens junction assembly |
| Biological Process | GO:0071392 | cellular response to estradiol stimulus |
| Biological Process | GO:0006351 | DNA-templated transcription |
| Biological Process | GO:0060644 | mammary gland epithelial cell differentiation |
| Biological Process | GO:0045892 | negative regulation of DNA-templated transcription |
| Biological Process | GO:0034111 | negative regulation of homotypic cell-cell adhesion |
| Biological Process | GO:0030335 | positive regulation of cell migration |
| Biological Process | GO:0008284 | positive regulation of cell population proliferation |
| Biological Process | GO:0010718 | positive regulation of epithelial to mesenchymal transition |
| Biological Process | GO:0033601 | positive regulation of mammary gland epithelial cell proliferation |
| Biological Process | GO:0060828 | regulation of canonical Wnt signaling pathway |
| Biological Process | GO:0051726 | regulation of cell cycle |
| Biological Process | GO:0006355 | regulation of DNA-templated transcription |
| Biological Process | GO:0017015 | regulation of transforming growth factor beta receptor signaling pathway |
Reference
PMID: N/A