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Overview

Uniprot IDQ9H8G2
Protein NameCaspase activity and apoptosis inhibitor 1
Gene NameCAAP1
OrganismHomo sapiens

Kla Sites from experimental identification

Position Flanking peptide
176 NCSIEEIKKLCQEQL

Function

Anti-apoptotic protein that modulates a caspase-10 dependent mitochondrial caspase-3/9 feedback amplification loop

Protein Sequence

10 MTGKKSSREK 20 RRKRSSQEAA 30 AALAAPDIVP 40 ALASGSSGST 50 SGCGSAGGCG 60 SVSCCGNANF 70 SGSVTGGGSG 80 GSCWGGSSVE 90 RSERRKRRST 100 DSSSVSGSLQ 110 QETKYILPTL 120 EKELFLAEHS 130 DLEEGGLDLT 140 VSLKPVSFYI 150 SDKKEMLQQC 160 FCIIGEKKLQ 170 KMLPDVLKNC 180 SIEEIKKLCQ 190 EQLELLSEKK 200 ILKILEGDNG 210 MDSDMEEEAD 220 DGSKMGSDLV 230 SQQDICIDSA 240 SSVRENKQPE 250 GLELKQGKGE 260 DSDVLSINAD 270 AYDSDIEGPC 280 NEEAAAPEAP 290 ENTVQSEAGQ 300 IDDLEKDIEK 310 SVNEILGLAE 320 SSPNEPKAAT 330 LAVPPPEDVQ 340 PSAQQLELLE 350 LEMRARAIKA 360 LMKAGDIKKP A

Gene Ontology

Classification GO ID Description
Biological Process GO:0006915 apoptotic process
Biological Process GO:0043066 negative regulation of apoptotic process

Reference

PMID: N/A