Search Results

Overview

Uniprot ID	Q9H8H0
Protein Name	Nucleolar protein 11
Gene Name	NOL11
Organism	Homo sapiens

Kla Sites from experimental identification

Position	Flanking peptide
386	RRILRRRKIEVSLQP

Function

Ribosome biogenesis factor. May be required for both optimal rDNA transcription and small subunit (SSU) pre-rRNA processing at sites A', A0, 1 and 2b

Protein Sequence

10 MAALEEEFTL 20 SSVVLSAGPE 30 GLLGVEQSDK 40 TDQFLVTDSG 50 RTVILYKVSD 60 QKPLGSWSVK 70 QGQIITCPAV 80 CNFQTGEYVV 90 VHDNKVLRIW 100 NNEDVNLDKV 110 FKATLSAEVY 120 RILSVQGTEP 130 LVLFKEGAVR 140 GLEALLADPQ 150 QKIETVISDE 160 EVIKWTKFFV 170 VFRHPVLIFI 180 TEKHGNYFAY 190 VQMFNSRILT 200 KYTLLLGQDE 210 NSVIKSFTAS 220 VDRKFISLMS 230 LSSDGCIYET 240 LIPIRPADPE 250 KNQSLVKSLL 260 LKAVVSGNAR 270 NGVALTALDQ 280 DHVAVLGSPL 290 AASKECLSVW 300 NIKFQTLQTS 310 KELPQGTSGQ 320 LWYYGEHLFM 330 LHGKSLTVIP 340 YKCEVSSLAG 350 ALGKLKHSQD 360 PGTHVVSHFV 370 NWETPQGCGL 380 GFQNSEQSRR 390 ILRRRKIEVS 400 LQPEVPPSKQ 410 LLSTIMKDSE 420 KHIEVEVRKF 430 LALKQTPDFH 440 TVIGDTVTGL 450 LERCKAEPSF 460 YPRNCLMQLI 470 QTHVLSYSLC 480 PDLMEIALKK 490 KDVQLLQLCL 500 QQFPDIPESV 510 TCACLKIFLS 520 IGDDSLQETD 530 VNMESVFDYS 540 INSVHDEKME 550 EQTEILQNGF 560 NPEEDKCNNC 570 DQELNKKPQD 580 ETKESTSCPV 590 VQKRAALLNA 600 ILHSAYSETF 610 LLPHLKDIPA 620 QHITLFLKYL 630 YFLYLKCSEN 640 ATMTLPGIHP 650 PTLNQIMDWI 660 CLLLDANFTV 670 VVMMPEAKRL 680 LINLYKLVKS 690 QISVYSELNK 700 IEVSFRELQK 710 LNQEKNNRGL YSIEVLELF

Gene Ontology

Classification	GO ID	Description
Cellular Component	GO:0005730	nucleolus
Cellular Component	GO:0005654	nucleoplasm
Cellular Component	GO:0034455	t-UTP complex
Molecular Function	GO:0003723	RNA binding
Biological Process	GO:0006351	DNA-templated transcription
Biological Process	GO:0030490	maturation of SSU-rRNA
Biological Process	GO:1901838	positive regulation of transcription of nucleolar large rRNA by RNA polymerase I

Reference

[1] Wu Q, Li Z, Gong T, Zheng X, Zhou X et al.. Porphyromonas gingivalis infection induces lysine lactylation reprogramming in human umbilical vein endothelial cells.. Front Cell Infect Microbiol 16:1706727. 2026. PMID: 41696360.