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Overview

Uniprot IDQ9H981
Protein NameActin-related protein 8
Gene NameACTR8
OrganismHomo sapiens

Kla Sites from experimental identification

Position Flanking peptide
431 YLLATQSKQEQSAKA

Function

Plays an important role in the functional organization of mitotic chromosomes. Exhibits low basal ATPase activity, and unable to polymerize

Protein Sequence

10 MTQAEKGDTE 20 NGKEKGGEKE 30 KEQRGVKRPI 40 VPALVPESLQ 50 EQIQSNFIIV 60 IHPGSTTLRI 70 GRATDTLPAS 80 IPHVIARRHK 90 QQGQPLYKDS 100 WLLREGLNKP 110 ESNEQRQNGL 120 KMVDQAIWSK 130 KMSNGTRRIP 140 VSPEQARSYN 150 KQMRPAILDH 160 CSGNKWTNTS 170 HHPEYLVGEE 180 ALYVNPLDCY 190 NIHWPIRRGQ 200 LNIHPGPGGS 210 LTAVLADIEV 220 IWSHAIQKYL 230 EIPLKDLKYY 240 RCILLIPDIY 250 NKQHVKELVN 260 MILMKMGFSG 270 IVVHQESVCA 280 TYGSGLSSTC 290 IVDVGDQKTS 300 VCCVEDGVSH 310 RNTRLCLAYG 320 GSDVSRCFYW 330 LMQRAGFPYR 340 ECQLTNKMDC 350 LLLQHLKETF 360 CHLDQDISGL 370 QDHEFQIRHP 380 DSPALLYQFR 390 LGDEKLQAPM 400 ALFYPATFGI 410 VGQKMTTLQH 420 RSQGDPEDPH 430 DEHYLLATQS 440 KQEQSAKATA 450 DRKSASKPIG 460 FEGDLRGQSS 470 DLPERLHSQE 480 VDLGSAQGDG 490 LMAGNDSEEA 500 LTALMSRKTA 510 ISLFEGKALG 520 LDKAILHSID 530 CCSSDDTKKK 540 MYSSILVVGG 550 GLMFHKAQEF 560 LQHRILNKMP 570 PSFRRIIENV 580 DVITRPKDMD 590 PRLIAWKGGA 600 VLACLDTTQE 610 LWIYQREWQR 620 FGVRMLRERA AFVW

Gene Ontology

Classification GO ID Description
Cellular Component GO:0031011 Ino80 complex
Cellular Component GO:0005654 nucleoplasm
Cellular Component GO:0005634 nucleus
Molecular Function GO:0005524 ATP binding
Molecular Function GO:0003729 mRNA binding
Biological Process GO:0051301 cell division
Biological Process GO:0006338 chromatin remodeling
Biological Process GO:0006310 DNA recombination
Biological Process GO:0006351 DNA-templated transcription
Biological Process GO:0006302 double-strand break repair
Biological Process GO:0045739 positive regulation of DNA repair
Biological Process GO:0045893 positive regulation of DNA-templated transcription
Biological Process GO:1904507 positive regulation of telomere maintenance in response to DNA damage
Biological Process GO:0051726 regulation of cell cycle
Biological Process GO:0033044 regulation of chromosome organization
Biological Process GO:0006275 regulation of DNA replication
Biological Process GO:0060382 regulation of DNA strand elongation
Biological Process GO:0006355 regulation of DNA-templated transcription
Biological Process GO:0045995 regulation of embryonic development
Biological Process GO:0000723 telomere maintenance

Reference

PMID: N/A