Search Results
Overview
| Uniprot ID | Q9H9A5 |
|---|---|
| Protein Name | CCR4-NOT transcription complex subunit 10 |
| Gene Name | CNOT10 |
| Organism | Homo sapiens |
Kla Sites from experimental identification
| Position | Flanking peptide |
|---|---|
| 507 | SSETCSSKSHDGDKF |
Function
Component of the CCR4-NOT complex which is one of the major cellular mRNA deadenylases and is linked to various cellular processes including bulk mRNA degradation, miRNA-mediated repression, translational repression during translational initiation and general transcription regulation. Additional complex functions may be a consequence of its influence on mRNA expression. Is not required for association of CNOT7 to the CCR4-NOT complex
Protein Sequence
10
MAADKPADQG
20
AEKHEGTGQS
30
SGITDQEKEL
40
STNAFQAFTS
50
GNYDACLQHL
60
ACLQDINKDD
70
YKIILNTAVA
80
EFFKSNQTTT
90
DNLRQTLNQL
100
KNQVHSAVEE
110
MDGLDDVENS
120
MLYYNQAVIL
130
YHLRQYTEAI
140
SVGEKLYQFI
150
EPFEEKFAQA
160
VCFLLVDLYI
170
LTYQAEKALH
180
LLAVLEKMIS
190
QGNNNKNGKN
200
ETGNNNNKDG
210
SNHKAESGAL
220
IEAAKSKIHQ
230
YKVRAYIQMK
240
SLKACKREIK
250
SVMNTAGNSA
260
PSLFLKSNFE
270
YLRGNYRKAV
280
KLLNSSNIAE
290
HPGFMKTGEC
300
LRCMFWNNLG
310
CIHFAMSKHN
320
LGIFYFKKAL
330
QENDNVCAQL
340
SAGSTDPGKK
350
FSGRPMCTLL
360
TNKRYELLYN
370
CGIQLLHIGR
380
PLAAFECLIE
390
AVQVYHANPR
400
LWLRLAECCI
410
AANKGTSEQE
420
TKGLPSKKGI
430
VQSIVGQGYH
440
RKIVLASQSI
450
QNTVYNDGQS
460
SAIPVASMEF
470
AAICLRNALL
480
LLPEEQQDPK
490
QENGAKNSNQ
500
LGGNTESSES
510
SETCSSKSHD
520
GDKFIPAPPS
530
SPLRKQELEN
540
LKCSILACSA
550
YVALALGDNL
560
MALNHADKLL
570
QQPKLSGSLK
580
FLGHLYAAEA
590
LISLDRISDA
600
ITHLNPENVT
610
DVSLGISSNE
620
QDQGSDKGEN
630
EAMESSGKRA
640
PQCYPSSVNS
650
ARTVMLFNLG
660
SAYCLRSEYD
670
KARKCLHQAA
680
SMIHPKEVPP
690
EAILLAVYLE
700
LQNGNTQLAL
710
QIIKRNQLLP
720
AVKTHSEVRK
730
KPVFQPVHPI
740
QPIQMPAFTT
VQRK
Gene Ontology
| Classification | GO ID | Description |
|---|---|---|
| Cellular Component | GO:0030014 | CCR4-NOT complex |
| Cellular Component | GO:0005829 | cytosol |
| Cellular Component | GO:0016020 | membrane |
| Cellular Component | GO:0005634 | nucleus |
| Biological Process | GO:0006351 | DNA-templated transcription |
| Biological Process | GO:0006402 | mRNA catabolic process |
| Biological Process | GO:0017148 | negative regulation of translation |
| Biological Process | GO:0000289 | nuclear-transcribed mRNA poly(A) tail shortening |
| Biological Process | GO:0031047 | regulatory ncRNA-mediated gene silencing |
Reference
PMID: N/A