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Overview

Uniprot IDQ9H9J2
Protein NameLarge ribosomal subunit protein mL44
Gene NameMRPL44
OrganismHomo sapiens

Kla Sites from experimental identification

Position Flanking peptide
303 AARVALRKLYGFTEN

Function

Component of the 39S subunit of mitochondrial ribosome (PubMed:23315540). May have a function in the assembly/stability of nascent mitochondrial polypeptides exiting the ribosome (PubMed:23315540)

Protein Sequence

10 MASGLVRLLQ 20 QGHRCLLAPV 30 APKLVPPVRG 40 VKKGFRAAFR 50 FQKELERQRL 60 LRCPPPPVRR 70 SEKPNWDYHA 80 EIQAFGHRLQ 90 ENFSLDLLKT 100 AFVNSCYIKS 110 EEAKRQQLGI 120 EKEAVLLNLK 130 SNQELSEQGT 140 SFSQTCLTQF 150 LEDEYPDMPT 160 EGIKNLVDFL 170 TGEEVVCHVA 180 RNLAVEQLTL 190 SEEFPVPPAV 200 LQQTFFAVIG 210 ALLQSSGPER 220 TALFIRDFLI 230 TQMTGKELFE 240 MWKIINPMGL 250 LVEELKKRNV 260 SAPESRLTRQ 270 SGGTTALPLY 280 FVGLYCDKKL 290 IAEGPGETVL 300 VAEEEAARVA 310 LRKLYGFTEN 320 RRPWNYSKPK 330 ETLRAEKSIT AS

Gene Ontology

Classification GO ID Description
Cellular Component GO:0005743 mitochondrial inner membrane
Cellular Component GO:0005762 mitochondrial large ribosomal subunit
Cellular Component GO:0005739 mitochondrion
Cellular Component GO:0005634 nucleus
Molecular Function GO:0003725 double-stranded RNA binding
Molecular Function GO:0003723 RNA binding
Biological Process GO:0032543 mitochondrial translation
Biological Process GO:0070125 mitochondrial translational elongation
Biological Process GO:0006417 regulation of translation
Biological Process GO:0006396 RNA processing

Reference

[1] Wu Q, Li Z, Gong T, Zheng X, Zhou X et al.. Porphyromonas gingivalis infection induces lysine lactylation reprogramming in human umbilical vein endothelial cells.. Front Cell Infect Microbiol 16:1706727. 2026. PMID: 41696360.