Search Results

Overview

Uniprot IDQ9HA38
Protein NameZinc finger matrin-type protein 3
Gene NameZMAT3
OrganismHomo sapiens

Kla Sites from experimental identification

Position Flanking peptide
271 HLESKQHKSKVSEQR
273 ESKQHKSKVSEQRYR

Function

Acts as a bona fide target gene of p53/TP53. May play a role in the TP53-dependent growth regulatory pathway. May contribute to TP53-mediated apoptosis by regulation of TP53 expression and translocation to the nucleus and nucleolus

Protein Sequence

10 MILLQHAVLP 20 PPKQPSPSPP 30 MSVATRSTGT 40 LQLPPQKPFG 50 QEASLPLAGE 60 EELSKGGEQD 70 CALEELCKPL 80 YCKLCNVTLN 90 SAQQAQAHYQ 100 GKNHGKKLRN 110 YYAANSCPPP 120 ARMSNVVEPA 130 ATPVVPVPPQ 140 MGSFKPGGRV 150 ILATENDYCK 160 LCDASFSSPA 170 VAQAHYQGKN 180 HAKRLRLAEA 190 QSNSFSESSE 200 LGQRRARKEG 210 NEFKMMPNRR 220 NMYTVQNNSA 230 GPYFNPRSRQ 240 RIPRDLAMCV 250 TPSGQFYCSM 260 CNVGAGEEME 270 FRQHLESKQH 280 KSKVSEQRYR NEMENLGYV

Gene Ontology

Classification GO ID Description
Cellular Component GO:0005730 nucleolus
Cellular Component GO:0005654 nucleoplasm
Molecular Function GO:0003723 RNA binding
Molecular Function GO:0008270 zinc ion binding
Biological Process GO:0006915 apoptotic process
Biological Process GO:0006974 DNA damage response
Biological Process GO:0015031 protein transport

Reference

[1] Cheng Z, Huang H, Li M, Chen Y. Proteomic analysis identifies PFKP lactylation in SW480 colon cancer cells.. iScience 27(1):108645. 2024 Jan 19. PMID: 38155775.