Search Results
Overview
| Uniprot ID | Q9HAT0 |
|---|---|
| Protein Name | Ropporin-1A |
| Gene Name | ROPN1 |
| Organism | Homo sapiens |
Kla Sites from experimental identification
| Position | Flanking peptide |
|---|---|
| 73 | ELTPELLKILHSQVA |
Function
Important for male fertility. With ROPN1L, involved in fibrous sheath integrity and sperm motility, plays a role in PKA-dependent signaling processes required for spermatozoa capacitation
Protein Sequence
10
MAQTDKPTCI
20
PPELPKMLKE
30
FAKAAIRVQP
40
QDLIQWAADY
50
FEALSRGETP
60
PVRERSERVA
70
LCNRAELTPE
80
LLKILHSQVA
90
GRLIIRAEEL
100
AQMWKVVNLP
110
TDLFNSVMNV
120
GRFTEEIEWL
130
KFLALACSAL
140
GVTITKTLKI
150
VCEVLSCDHN
160
GGSPRIPFST
170
FQFLYTYIAK
180
VDGEISASHV
190
SRMLNYMEQE
200
VIGPDGIITV
210
NDFTQNPRVQ
LE
Gene Ontology
| Classification | GO ID | Description |
|---|---|---|
| Cellular Component | GO:0005737 | cytoplasm |
| Cellular Component | GO:0031514 | motile cilium |
| Cellular Component | GO:0005634 | nucleus |
| Molecular Function | GO:0042802 | identical protein binding |
| Biological Process | GO:0044782 | cilium organization |
| Biological Process | GO:0030317 | flagellated sperm motility |
| Biological Process | GO:0061512 | protein localization to cilium |
| Biological Process | GO:0048240 | sperm capacitation |
Reference
[1] Yan M, Tu H, Tang S, Gai Z, Shi Q et al.. Lactylated Proteomic Analysis Reveals Functional Implications of Lysine Lactylation In Asthenozoospermia.. Mol Cell Proteomics 24(12):101439. 2025 Dec. PMID: 41192556.