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Overview

Uniprot IDQ9HBI0
Protein NameGamma-parvin
Gene NamePARVG
OrganismHomo sapiens

Kla Sites from experimental identification

Position Flanking peptide
213 PEKVNAVKEAIVNFV
223 IVNFVNQKLDRLGLS

Function

Plays a role with ILK in promoting the cell adhesion and spreading of leukocytes

Protein Sequence

10 MEPEFLYDLL 20 QLPKGVEPPA 30 EEELSKGGKK 40 KYLPPTSRKD 50 PKFEELQKVL 60 MEWINATLLP 70 EHIVVRSLEE 80 DMFDGLILHH 90 LFQRLAALKL 100 EAEDIALTAT 110 SQKHKLTVVL 120 EAVNRSLQLE 130 EWQAKWSVES 140 IFNKDLLSTL 150 HLLVALAKRF 160 QPDLSLPTNV 170 QVEVITIEST 180 KSGLKSEKLV 190 EQLTEYSTDK 200 DEPPKDVFDE 210 LFKLAPEKVN 220 AVKEAIVNFV 230 NQKLDRLGLS 240 VQNLDTQFAD 250 GVILLLLIGQ 260 LEGFFLHLKE 270 FYLTPNSPAE 280 MLHNVTLALE 290 LLKDEGLLSC 300 PVSPEDIVNK 310 DAKSTLRVLY 320 GLFCKHTQKA 330 HRDRTPHGAP N

Gene Ontology

Classification GO ID Description
Cellular Component GO:0015629 actin cytoskeleton
Cellular Component GO:0005737 cytoplasm
Cellular Component GO:0005856 cytoskeleton
Cellular Component GO:0005925 focal adhesion
Cellular Component GO:0005886 plasma membrane
Molecular Function GO:0003779 actin binding
Biological Process GO:0030036 actin cytoskeleton organization
Biological Process GO:0030031 cell projection assembly
Biological Process GO:0007160 cell-matrix adhesion
Biological Process GO:0071963 establishment or maintenance of cell polarity regulating cell shape
Biological Process GO:0034446 substrate adhesion-dependent cell spreading

Reference

[1] Cheng Z, Huang H, Li M, Chen Y. Proteomic analysis identifies PFKP lactylation in SW480 colon cancer cells.. iScience 27(1):108645. 2024 Jan 19. PMID: 38155775.