Search Results

Overview

Uniprot ID	Q9HBR0
Protein Name	Solute carrier family 38 member 10
Gene Name	SLC38A10
Organism	Homo sapiens

Kla Sites from experimental identification

Position	Flanking peptide
422	GEAEGLMKVEAARLS
713	KEQQVQQKRLLDQQE

Function

Facilitates bidirectional transport of amino acids. May act as a glutamate sensor that regulates glutamate-glutamine cycle and mTOR signaling in the brain. The transport mechanism remains to be elucidated

Protein Sequence

10 MTAAAASNWG 20 LITNIVNSIV 30 GVSVLTMPFC 40 FKQCGIVLGA 50 LLLVFCSWMT 60 HQSCMFLVKS 70 ASLSKRRTYA 80 GLAFHAYGKA 90 GKMLVETSMI 100 GLMLGTCIAF 110 YVVIGDLGSN 120 FFARLFGFQV 130 GGTFRMFLLF 140 AVSLCIVLPL 150 SLQRNMMASI 160 QSFSAMALLF 170 YTVFMFVIVL 180 SSLKHGLFSG 190 QWLRRVSYVR 200 WEGVFRCIPI 210 FGMSFACQSQ 220 VLPTYDSLDE 230 PSVKTMSSIF 240 ASSLNVVTTF 250 YVMVGFFGYV 260 SFTEATAGNV 270 LMHFPSNLVT 280 EMLRVGFMMS 290 VAVGFPMMIL 300 PCRQALSTLL 310 CEQQQKDGTF 320 AAGGYMPPLR 330 FKALTLSVVF 340 GTMVGGILIP 350 NVETILGLTG 360 ATMGSLICFI 370 CPALIYKKIH 380 KNALSSQVVL 390 WVGLGVLVVS 400 TVTTLSVSEE 410 VPEDLAEEAP 420 GGRLGEAEGL 430 MKVEAARLSA 440 QDPVVAVAED 450 GREKPKLPKE 460 REELEQAQIK 470 GPVDVPGRED 480 GKEAPEEAQL 490 DRPGQGIAVP 500 VGEAHRHEPP 510 VPHDKVVVDE 520 GQDREVPEEN 530 KPPSRHAGGK 540 APGVQGQMAP 550 PLPDSEREKQ 560 EPEQGEVGKR 570 PGQAQALEEA 580 GDLPEDPQKV 590 PEADGQPAVQ 600 PAKEDLGPGD 610 RGLHPRPQAV 620 LSEQQNGLAV 630 GGGEKAKGGP 640 PPGNAAGDTG 650 QPAEDSDHGG 660 KPPLPAEKPA 670 PGPGLPPEPR 680 EQRDVERAGG 690 NQAASQLEEA 700 GRAEMLDHAV 710 LLQVIKEQQV 720 QQKRLLDQQE 730 KLLAVIEEQH 740 KEIHQQRQED 750 EEDKPRQVEV 760 HQEPGAAVPR 770 GQEAPEGKAR 780 ETVENLPPLP 790 LDPVLRAPGG 800 RPAPSQDLNQ 810 RSLEHSEGPV 820 GRDPAGPPDG 830 GPDTEPRAAQ 840 AKLRDGQKDA 850 APRAAGTVKE 860 LPKGPEQVPV 870 PDPAREAGGP 880 EERLAEEFPG 890 QSQDVTGGSQ 900 DRKKPGKEVA 910 ATGTSILKEA 920 NWLVAGPGAE 930 TGDPRMKPKQ 940 VSRDLGLAAD 950 LPGGAEGAAA 960 QPQAVLRQPE 970 LRVISDGEQG 980 GQQGHRLDHG 990 GHLEMRKARG 1000 GDHVPVSHEQ 1010 PRGGEDAAVQ 1020 EPRQRPEPEL 1030 GLKRAVPGGQ 1040 RPDNAKPNRD 1050 LKLQAGSDLR 1060 RRRRDLGPHA 1070 EGQLAPRDGV 1080 IIGLNPLPDV 1090 QVNDLRGALD 1100 AQLRQAAGGA 1110 LQVVHSRQLR QAPGPPEES

Gene Ontology

Classification	GO ID	Description
Cellular Component	GO:0005794	Golgi apparatus
Cellular Component	GO:0016020	membrane
Molecular Function	GO:0015179	L-amino acid transmembrane transporter activity
Biological Process	GO:0003333	amino acid transmembrane transport

Reference

[1] Hong H, Chen X, Wang H, Gu X, Yuan Y et al.. Global profiling of protein lysine lactylation and potential target modified protein analysis in hepatocellular carcinoma.. Proteomics 23(9):e2200432. 2023 May. PMID: 36625413.