Search Results
Overview
| Uniprot ID | Q9HBZ2 |
|---|---|
| Protein Name | Aryl hydrocarbon receptor nuclear translocator 2 |
| Gene Name | ARNT2 |
| Organism | Homo sapiens |
Kla Sites from experimental identification
| Position | Flanking peptide |
|---|---|
| 214 | TGRILDLKTGTVKKE |
Function
Transcription factor that plays a role in the development of the hypothalamo-pituitary axis, postnatal brain growth, and visual and renal function (PubMed:24022475). Specifically recognizes the xenobiotic response element (XRE)
Protein Sequence
10
MATPAAVNPP
20
EMASDIPGSV
30
TLPVAPMAAT
40
GQVRMAGAMP
50
ARGGKRRSGM
60
DFDDEDGEGP
70
SKFSRENHSE
80
IERRRRNKMT
90
QYITELSDMV
100
PTCSALARKP
110
DKLTILRMAV
120
SHMKSMRGTG
130
NKSTDGAYKP
140
SFLTEQELKH
150
LILEAADGFL
160
FVVAAETGRV
170
IYVSDSVTPV
180
LNQPQSEWFG
190
STLYEQVHPD
200
DVEKLREQLC
210
TSENSMTGRI
220
LDLKTGTVKK
230
EGQQSSMRMC
240
MGSRRSFICR
250
MRCGNAPLDH
260
LPLNRITTMR
270
KRFRNGLGPV
280
KEGEAQYAVV
290
HCTGYIKAWP
300
PAGMTIPEED
310
ADVGQGSKYC
320
LVAIGRLQVT
330
SSPVCMDMNG
340
MSVPTEFLSR
350
HNSDGIITFV
360
DPRCISVIGY
370
QPQDLLGKDI
380
LEFCHPEDQS
390
HLRESFQQVV
400
KLKGQVLSVM
410
YRFRTKNREW
420
MLIRTSSFTF
430
QNPYSDEIEY
440
IICTNTNVKQ
450
LQQQQAELEV
460
HQRDGLSSYD
470
LSQVPVPNLP
480
AGVHEAGKSV
490
EKADAIFSQE
500
RDPRFAEMFA
510
GISASEKKMM
520
SSASAAGTQQ
530
IYSQGSPFPS
540
GHSGKAFSSS
550
VVHVPGVNDI
560
QSSSSTGQNM
570
SQISRQLNQS
580
QVAWTGSRPP
590
FPGQQIPSQS
600
SKTQSSPFGI
610
GTSHTYPADP
620
SSYSPLSSPA
630
TSSPSGNAYS
640
SLANRTPGFA
650
ESGQSSGQFQ
660
GRPSEVWSQW
670
QSQHHGQQSG
680
EQHSHQQPGQ
690
TEVFQDMLPM
700
PGDPTQGTGN
710
YNIEDFADLG
MFPPFSE
Gene Ontology
| Classification | GO ID | Description |
|---|---|---|
| Cellular Component | GO:0034751 | aryl hydrocarbon receptor complex |
| Cellular Component | GO:0000785 | chromatin |
| Cellular Component | GO:0005737 | cytoplasm |
| Cellular Component | GO:0005654 | nucleoplasm |
| Cellular Component | GO:0005634 | nucleus |
| Cellular Component | GO:0005667 | transcription regulator complex |
| Molecular Function | GO:0017162 | aryl hydrocarbon receptor binding |
| Molecular Function | GO:0001228 | DNA-binding transcription activator activity, RNA polymerase II-specific |
| Molecular Function | GO:0003700 | DNA-binding transcription factor activity |
| Molecular Function | GO:0000981 | DNA-binding transcription factor activity, RNA polymerase II-specific |
| Molecular Function | GO:0046982 | protein heterodimerization activity |
| Molecular Function | GO:0044877 | protein-containing complex binding |
| Molecular Function | GO:0000978 | RNA polymerase II cis-regulatory region sequence-specific DNA binding |
| Molecular Function | GO:1990837 | sequence-specific double-stranded DNA binding |
| Biological Process | GO:0007420 | brain development |
| Biological Process | GO:0007417 | central nervous system development |
| Biological Process | GO:0006351 | DNA-templated transcription |
| Biological Process | GO:0001701 | in utero embryonic development |
| Biological Process | GO:0043066 | negative regulation of apoptotic process |
| Biological Process | GO:0008284 | positive regulation of cell population proliferation |
| Biological Process | GO:0045893 | positive regulation of DNA-templated transcription |
| Biological Process | GO:0045944 | positive regulation of transcription by RNA polymerase II |
| Biological Process | GO:0006355 | regulation of DNA-templated transcription |
| Biological Process | GO:0006357 | regulation of transcription by RNA polymerase II |
| Biological Process | GO:0032355 | response to estradiol |
| Biological Process | GO:0001666 | response to hypoxia |
| Biological Process | GO:0006805 | xenobiotic metabolic process |
Reference
PMID: N/A