Search Results

Overview

Uniprot IDQ9N1F5
Protein NameGlutathione S-transferase omega-1
Gene NameGSTO1
OrganismSus scrofa

Kla Sites from experimental identification

Position Flanking peptide
101 DEAYPGKKLLPDDPY
11 GSARSLGKGSAPPGP
110 LPDDPYEKACQKMVF
114 PYEKACQKMVFELSS
143 EADCSGLKEELRKEF
152 ELRKEFSKLEEVLTK
159 KLEEVLTKKKTTYFG
198 ECIDHTPKLKLWMAA
45 TLLVLNAKGIRHQVI
59 ININLKNKPEWFFQK

Function

Exhibits glutathione-dependent thiol transferase and dehydroascorbate reductase activities. Has S-(phenacyl)glutathione reductase activity. Also has glutathione S-transferase activity. Participates in the biotransformation of inorganic arsenic and reduces monomethylarsonic acid (MMA) and dimethylarsonic acid

Protein Sequence

10 MSGGSARSLG 20 KGSAPPGPVP 30 EGLIRVYSMR 40 FCPFAQRTLL 50 VLNAKGIRHQ 60 VININLKNKP 70 EWFFQKNPSG 80 LVPVLENSQG 90 QLIYESAITC 100 EYLDEAYPGK 110 KLLPDDPYEK 120 ACQKMVFELS 130 SKVPPLLIRF 140 IRRENEADCS 150 GLKEELRKEF 160 SKLEEVLTKK 170 KTTYFGGSSL 180 SMIDYLIWPW 190 FERLEALELN 200 ECIDHTPKLK 210 LWMAAMMKDP 220 AVSALHIEPR 230 DLRAFNDLYL 240 QNSPEACDYG L

Gene Ontology

Classification GO ID Description
Cellular Component GO:0005737 cytoplasm
Cellular Component GO:0005829 cytosol
Molecular Function GO:0045174 glutathione dehydrogenase (ascorbate) activity
Molecular Function GO:0004364 glutathione transferase activity
Molecular Function GO:0050610 methylarsonate reductase activity
Molecular Function GO:0016491 oxidoreductase activity
Biological Process GO:0071243 cellular response to arsenic-containing substance
Biological Process GO:0006749 glutathione metabolic process
Biological Process GO:0019852 L-ascorbic acid metabolic process
Biological Process GO:0042178 xenobiotic catabolic process

Reference

[1] Fan S, Zhou R, Wen H, Ye H, Ma S et al.. Global profiling of protein lactylome in porcine granulosa cells.. J Ovarian Res 18(1):177. 2025 Aug 8. PMID: 40781717.