Search Results
Overview
| Uniprot ID | Q9NP66 |
|---|---|
| Protein Name | High mobility group protein 20A |
| Gene Name | HMG20A |
| Organism | Homo sapiens |
Kla Sites from experimental identification
| Position | Flanking peptide |
|---|---|
| 177 | YQKTEAYKVFSRKTQ |
Function
Plays a role in neuronal differentiation as chromatin-associated protein. Acts as inhibitor of HMG20B. Overcomes the repressive effects of the neuronal silencer REST and induces the activation of neuronal-specific genes. Involved in the recruitment of the histone methyltransferase KMT2A/MLL1 and consequent increased methylation of histone H3 lysine 4 (By similarity)
Protein Sequence
10
MENLMTSSTL
20
PPLFADEDGS
30
KESNDLATTG
40
LNHPEVPYSS
50
GATSSTNNPE
60
FVEDLSQGQL
70
LQSESSNAAE
80
GNEQRHEDEQ
90
RSKRGGWSKG
100
RKRKKPLRDS
110
NAPKSPLTGY
120
VRFMNERREQ
130
LRAKRPEVPF
140
PEITRMLGNE
150
WSKLPPEEKQ
160
RYLDEADRDK
170
ERYMKELEQY
180
QKTEAYKVFS
190
RKTQDRQKGK
200
SHRQDAARQA
210
THDHEKETEV
220
KERSVFDIPI
230
FTEEFLNHSK
240
AREAELRQLR
250
KSNMEFEERN
260
AALQKHVESM
270
RTAVEKLEVD
280
VIQERSRNTV
290
LQQHLETLRQ
300
VLTSSFASMP
310
LPGSGETPTV
320
DTIDSYMNRL
330
HSIILANPQD
340
NENFIATVRE
VVNRLDR
Gene Ontology
| Classification | GO ID | Description |
|---|---|---|
| Cellular Component | GO:0005634 | nucleus |
| Molecular Function | GO:0003677 | DNA binding |
| Molecular Function | GO:0042802 | identical protein binding |
| Biological Process | GO:0006325 | chromatin organization |
| Biological Process | GO:0006351 | DNA-templated transcription |
| Biological Process | GO:0006355 | regulation of DNA-templated transcription |
| Biological Process | GO:0010468 | regulation of gene expression |
Reference
PMID: N/A