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Overview

Uniprot IDQ9NQ29
Protein NamePutative RNA-binding protein Luc7-like 1
Gene NameLUC7L
OrganismHomo sapiens

Kla Sites from experimental identification

Position Flanking peptide
357 RLESSNGKMASRRSE

Function

May bind to RNA via its Arg/Ser-rich domain

Protein Sequence

10 MSAQAQMRAL 20 LDQLMGTARD 30 GDETRQRVKF 40 TDDRVCKSHL 50 LDCCPHDILA 60 GTRMDLGECT 70 KIHDLALRAD 80 YEIASKERDL 90 FFELDAMDHL 100 ESFIAECDRR 110 TELAKKRLAE 120 TQEEISAEVS 130 AKAEKVHELN 140 EEIGKLLAKA 150 EQLGAEGNVD 160 ESQKILMEVE 170 KVRAKKKEAE 180 EEYRNSMPAS 190 SFQQQKLRVC 200 EVCSAYLGLH 210 DNDRRLADHF 220 GGKLHLGFIQ 230 IREKLDQLRK 240 TVAEKQEKRN 250 QDRLRRREER 260 EREERLSRRS 270 GSRTRDRRRS 280 RSRDRRRRRS 290 RSTSRERRKL 300 SRSRSRDRHR 310 RHRSRSRSHS 320 RGHRRASRDR 330 SAKYKFSRER 340 ASREESWESG 350 RSERGPPDWR 360 LESSNGKMAS 370 RRSEEKEAGE I

Gene Ontology

Classification GO ID Description
Cellular Component GO:0005685 U1 snRNP
Cellular Component GO:0071004 U2-type prespliceosome
Molecular Function GO:0042802 identical protein binding
Molecular Function GO:0003729 mRNA binding
Molecular Function GO:0050733 RS domain binding
Biological Process GO:0006376 mRNA splice site recognition

Reference

[1] Yang D, Yin J, Shan L, Yi X, Zhang W et al.. Identification of lysine-lactylated substrates in gastric cancer cells.. iScience 25(7):104630. 2022 Jul 15. PMID: 35800753.

[2] He C, Zhang J, Bai X, Lu C, Zhang K. Lysine lactylation-based insight to understanding the characterization of cervical cancer.. Biochim Biophys Acta Mol Basis Dis 1870(7):167356. 2024 Oct. PMID: 39025375.