Search Results
Overview
| Uniprot ID | Q9NQ55 |
|---|---|
| Protein Name | Suppressor of SWI4 1 homolog |
| Gene Name | PPAN |
| Organism | Homo sapiens |
Kla Sites from experimental identification
| Position | Flanking peptide |
|---|---|
| 217 | MKKLLQEKFPNMSRL |
| 346 | QREAHRKKSLEGMKK |
| 435 | RGRLCDQKFPKTKDK |
| 438 | LCDQKFPKTKDKSQG |
Function
May have a role in cell growth
Protein Sequence
10
MGQSGRSRHQ
20
KRARAQAQLR
30
NLEAYAANPH
40
SFVFTRGCTG
50
RNIRQLSLDV
60
RRVMEPLTAS
70
RLQVRKKNSL
80
KDCVAVAGPL
90
GVTHFLILSK
100
TETNVYFKLM
110
RLPGGPTLTF
120
QVKKYSLVRD
130
VVSSLRRHRM
140
HEQQFAHPPL
150
LVLNSFGPHG
160
MHVKLMATMF
170
QNLFPSINVH
180
KVNLNTIKRC
190
LLIDYNPDSQ
200
ELDFRHYSIK
210
VVPVGASRGM
220
KKLLQEKFPN
230
MSRLQDISEL
240
LATGAGLSES
250
EAEPDGDHNI
260
TELPQAVAGR
270
GNMRAQQSAV
280
RLTEIGPRMT
290
LQLIKVQEGV
300
GEGKVMFHSF
310
VSKTEEELQA
320
ILEAKEKKLR
330
LKAQRQAQQA
340
QNVQRKQEQR
350
EAHRKKSLEG
360
MKKARVGGSD
370
EEASGIPSRT
380
ASLELGEDDD
390
EQEDDDIEYF
400
CQAVGEAPSE
410
DLFPEAKQKR
420
LAKSPGRKRK
430
RWEMDRGRGR
440
LCDQKFPKTK
450
DKSQGAQARR
460
GPRGASRDGG
470
RGRGRGRPGK
RVA
Gene Ontology
| Classification | GO ID | Description |
|---|---|---|
| Cellular Component | GO:0005730 | nucleolus |
| Cellular Component | GO:0005634 | nucleus |
| Cellular Component | GO:0030687 | preribosome, large subunit precursor |
| Molecular Function | GO:0003723 | RNA binding |
| Molecular Function | GO:0019843 | rRNA binding |
| Biological Process | GO:0000463 | maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) |
Reference
[1] He C, Zhang J, Bai X, Lu C, Zhang K. Lysine lactylation-based insight to understanding the characterization of cervical cancer.. Biochim Biophys Acta Mol Basis Dis 1870(7):167356. 2024 Oct. PMID: 39025375.
[2] He J, Lai T, Zhou Z, Yang H, Lei Z et al.. Multiomics profiling reveals the involvement of protein lactylation in nonhomologous end joining pathway conferring radioresistance in lung adenocarcinoma cell.. Sci Rep 15(1):24651. 2025 Jul 9. PMID: 40634431.
[3] Wu Q, Li Z, Gong T, Zheng X, Zhou X et al.. Porphyromonas gingivalis infection induces lysine lactylation reprogramming in human umbilical vein endothelial cells.. Front Cell Infect Microbiol 16:1706727. 2026. PMID: 41696360.