Search Results

Overview

Uniprot ID	Q9NR46
Protein Name	Endophilin-B2
Gene Name	SH3GLB2
Organism	Homo sapiens

Kla Sites from experimental identification

Position	Flanking peptide
26	AVQFTEEKFGQAEKT
7	*MDFNMKKLASDAGI
79	VEEFLYEKLDRKVPS

Function

No function data available.

Protein Sequence

10 MDFNMKKLAS 20 DAGIFFTRAV 30 QFTEEKFGQA 40 EKTELDAHFE 50 NLLARADSTK 60 NWTEKILRQT 70 EVLLQPNPSA 80 RVEEFLYEKL 90 DRKVPSRVTN 100 GELLAQYMAD 110 AASELGPTTP 120 YGKTLIKVAE 130 AEKQLGAAER 140 DFIHTASISF 150 LTPLRNFLEG 160 DWKTISKERR 170 LLQNRRLDLD 180 ACKARLKKAK 190 AAEAKATTVP 200 DFQETRPRNY 210 ILSASASALW 220 NDEVDKAEQE 230 LRVAQTEFDR 240 QAEVTRLLLE 250 GISSTHVNHL 260 RCLHEFVKSQ 270 TTYYAQCYRH 280 MLDLQKQLGR 290 FPGTFVGTTE 300 PASPPLSSTS 310 PTTAAATMPV 320 VPSVASLAPP 330 GEASLCLEEV 340 APPASGTRKA 350 RVLYDYEAAD 360 SSELALLADE 370 LITVYSLPGM 380 DPDWLIGERG 390 NKKGKVPVTY LELLS

Gene Ontology

Classification	GO ID	Description
Cellular Component	GO:0005737	cytoplasm
Cellular Component	GO:0005829	cytosol
Cellular Component	GO:0016020	membrane
Molecular Function	GO:0045296	cadherin binding
Molecular Function	GO:0042802	identical protein binding
Molecular Function	GO:0030674	protein-macromolecule adaptor activity
Biological Process	GO:0006897	endocytosis
Biological Process	GO:0061024	membrane organization

Reference

[1] Yang D, Yin J, Shan L, Yi X, Zhang W et al.. Identification of lysine-lactylated substrates in gastric cancer cells.. iScience 25(7):104630. 2022 Jul 15. PMID: 35800753.

[2] Yang Z, Yan C, Ma J, Peng P, Ren X et al.. Lactylome analysis suggests lactylation-dependent mechanisms of metabolic adaptation in hepatocellular carcinoma.. Nat Metab 5(1):61-79. 2023 Jan. PMID: 36593272.

[3] Shi CM, Wang QC, Li XL, Yang YH, Tang XY et al.. Global Profiling of Protein Lactylation in Human Hippocampi.. Proteomics Clin Appl 19(2):e202400061. 2025 Mar. PMID: 39610256.

[4] Guo X, Ren X, Yan C, Huang H. Quantitative Proteomics Reveals the Role of Lysine Lactylation in Lenalidomide-Resistance in Multiple Myeloma Cells.. ACS Chem Biol 20(7):1728-1738. 2025 Jul 18. PMID: 40590393.

[5] Wu Q, Li Z, Gong T, Zheng X, Zhou X et al.. Porphyromonas gingivalis infection induces lysine lactylation reprogramming in human umbilical vein endothelial cells.. Front Cell Infect Microbiol 16:1706727. 2026. PMID: 41696360.