Search Results
Overview
| Uniprot ID | Q9NRM6 |
|---|---|
| Protein Name | Interleukin-17 receptor B |
| Gene Name | IL17RB |
| Organism | Homo sapiens |
Kla Sites from experimental identification
| Position | Flanking peptide |
|---|---|
| 386 | VQWLATQKKAADKVV |
Function
Receptor for the pro-inflammatory cytokines IL17B and IL17E. May play a role in controlling the growth and/or differentiation of hematopoietic cells
Protein Sequence
10
MSLVLLSLAA
20
LCRSAVPREP
30
TVQCGSETGP
40
SPEWMLQHDL
50
IPGDLRDLRV
60
EPVTTSVATG
70
DYSILMNVSW
80
VLRADASIRL
90
LKATKICVTG
100
KSNFQSYSCV
110
RCNYTEAFQT
120
QTRPSGGKWT
130
FSYIGFPVEL
140
NTVYFIGAHN
150
IPNANMNEDG
160
PSMSVNFTSP
170
GCLDHIMKYK
180
KKCVKAGSLW
190
DPNITACKKN
200
EETVEVNFTT
210
TPLGNRYMAL
220
IQHSTIIGFS
230
QVFEPHQKKQ
240
TRASVVIPVT
250
GDSEGATVQL
260
TPYFPTCGSD
270
CIRHKGTVVL
280
CPQTGVPFPL
290
DNNKSKPGGW
300
LPLLLLSLLV
310
ATWVLVAGIY
320
LMWRHERIKK
330
TSFSTTTLLP
340
PIKVLVVYPS
350
EICFHHTICY
360
FTEFLQNHCR
370
SEVILEKWQK
380
KKIAEMGPVQ
390
WLATQKKAAD
400
KVVFLLSNDV
410
NSVCDGTCGK
420
SEGSPSENSQ
430
DLFPLAFNLF
440
CSDLRSQIHL
450
HKYVVVYFRE
460
IDTKDDYNAL
470
SVCPKYHLMK
480
DATAFCAELL
490
HVKQQVSAGK
500
RSQACHDGCC
SL
Gene Ontology
| Classification | GO ID | Description |
|---|---|---|
| Cellular Component | GO:0009986 | cell surface |
| Cellular Component | GO:0005737 | cytoplasm |
| Cellular Component | GO:0005576 | extracellular region |
| Cellular Component | GO:0016020 | membrane |
| Cellular Component | GO:0005886 | plasma membrane |
| Molecular Function | GO:0004896 | cytokine receptor activity |
| Molecular Function | GO:0030368 | interleukin-17 receptor activity |
| Biological Process | GO:0006952 | defense response |
| Biological Process | GO:0097400 | interleukin-17-mediated signaling pathway |
| Biological Process | GO:0032736 | positive regulation of interleukin-13 production |
| Biological Process | GO:0032754 | positive regulation of interleukin-5 production |
| Biological Process | GO:0070534 | protein K63-linked ubiquitination |
| Biological Process | GO:0001558 | regulation of cell growth |
| Biological Process | GO:0010837 | regulation of keratinocyte proliferation |
| Biological Process | GO:0072538 | T-helper 17 type immune response |
Reference
[1] He C, Zhang J, Bai X, Lu C, Zhang K. Lysine lactylation-based insight to understanding the characterization of cervical cancer.. Biochim Biophys Acta Mol Basis Dis 1870(7):167356. 2024 Oct. PMID: 39025375.