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Overview

Uniprot IDQ9NS86
Protein NameLanC-like protein 2
Gene NameLANCL2
OrganismHomo sapiens

Kla Sites from experimental identification

Position Flanking peptide
10 ETMSKRLKLHLGGEA

Function

Necessary for abscisic acid (ABA) binding on the cell membrane and activation of the ABA signaling pathway in granulocytes

Protein Sequence

10 MGETMSKRLK 20 LHLGGEAEME 30 ERAFVNPFPD 40 YEAAAGALLA 50 SGAAEETGCV 60 RPPATTDEPG 70 LPFHQDGKII 80 HNFIRRIQTK 90 IKDLLQQMEE 100 GLKTADPHDC 110 SAYTGWTGIA 120 LLYLQLYRVT 130 CDQTYLLRSL 140 DYVKRTLRNL 150 NGRRVTFLCG 160 DAGPLAVGAV 170 IYHKLRSDCE 180 SQECVTKLLQ 190 LQRSVVCQES 200 DLPDELLYGR 210 AGYLYALLYL 220 NTEIGPGTVC 230 ESAIKEVVNA 240 IIESGKTLSR 250 EERKTERCPL 260 LYQWHRKQYV 270 GAAHGMAGIY 280 YMLMQPAAKV 290 DQETLTEMVK 300 PSIDYVRHKK 310 FRSGNYPSSL 320 SNETDRLVHW 330 CHGAPGVIHM 340 LMQAYKVFKE 350 EKYLKEAMEC 360 SDVIWQRGLL 370 RKGYGICHGT 380 AGNGYSFLSL 390 YRLTQDKKYL 400 YRACKFAEWC 410 LDYGAHGCRI 420 PDRPYSLFEG 430 MAGAIHFLSD 440 VLGPETSRFP 450 AFELDSSKRD

Gene Ontology

Classification GO ID Description
Cellular Component GO:0030864 cortical actin cytoskeleton
Cellular Component GO:0005829 cytosol
Cellular Component GO:0005654 nucleoplasm
Cellular Component GO:0005634 nucleus
Cellular Component GO:0005886 plasma membrane
Molecular Function GO:0005524 ATP binding
Molecular Function GO:0005525 GTP binding
Molecular Function GO:0032266 phosphatidylinositol-3-phosphate binding
Molecular Function GO:0070273 phosphatidylinositol-4-phosphate binding
Molecular Function GO:0010314 phosphatidylinositol-5-phosphate binding
Biological Process GO:0005975 carbohydrate metabolic process
Biological Process GO:0045892 negative regulation of DNA-templated transcription
Biological Process GO:0031179 peptide modification
Biological Process GO:0009789 positive regulation of abscisic acid-activated signaling pathway
Biological Process GO:0009787 regulation of abscisic acid-activated signaling pathway

Reference

[1] He C, Zhang J, Bai X, Lu C, Zhang K. Lysine lactylation-based insight to understanding the characterization of cervical cancer.. Biochim Biophys Acta Mol Basis Dis 1870(7):167356. 2024 Oct. PMID: 39025375.