Search Results
Overview
| Uniprot ID | Q9NU19 |
|---|---|
| Protein Name | TBC1 domain family member 22B |
| Gene Name | TBC1D22B |
| Organism | Homo sapiens |
Kla Sites from experimental identification
| Position | Flanking peptide |
|---|---|
| 106 | QVLENHSKLRVKPER |
| 55 | TVPLKNKKASSFHEF |
Function
May act as a GTPase-activating protein for Rab family protein(s)
Protein Sequence
10
MAAENSKQFW
20
KRSAKLPGSI
30
QPVYGAQHPP
40
LDPRLTKNFI
50
KERSKVNTVP
60
LKNKKASSFH
70
EFARNTSDAW
80
DIGDDEEEDF
90
SSPSFQTLNS
100
KVALATAAQV
110
LENHSKLRVK
120
PERSQSTTSD
130
VPANYKVIKS
140
SSDAQLSRNS
150
SDTCLRNPLH
160
KQQSLPLRPI
170
IPLVARISDQ
180
NASGAPPMTV
190
REKTRLEKFR
200
QLLSSQNTDL
210
DELRKCSWPG
220
VPREVRPITW
230
RLLSGYLPAN
240
TERRKLTLQR
250
KREEYFGFIE
260
QYYDSRNEEH
270
HQDTYRQIHI
280
DIPRTNPLIP
290
LFQQPLVQEI
300
FERILFIWAI
310
RHPASGYVQG
320
INDLVTPFFV
330
VFLSEYVEED
340
VENFDVTNLS
350
QDMLRSIEAD
360
SFWCMSKLLD
370
GIQDNYTFAQ
380
PGIQKKVKAL
390
EELVSRIDEQ
400
VHNHFRRYEV
410
EYLQFAFRWM
420
NNLLMRELPL
430
RCTIRLWDTY
440
QSEPEGFSHF
450
HLYVCAAFLI
460
KWRKEILDEE
470
DFQGLLMLLQ
480
NLPTIHWGNE
490
EIGLLLAEAY
500
RLKYMFADAP
NHYRR
Gene Ontology
| Classification | GO ID | Description |
|---|---|---|
| Cellular Component | GO:0005794 | Golgi apparatus |
| Molecular Function | GO:0071889 | 14-3-3 protein binding |
| Molecular Function | GO:0005096 | GTPase activator activity |
Reference
[1] He C, Zhang J, Bai X, Lu C, Zhang K. Lysine lactylation-based insight to understanding the characterization of cervical cancer.. Biochim Biophys Acta Mol Basis Dis 1870(7):167356. 2024 Oct. PMID: 39025375.
[2] Chao L, Xu Y, Yang Y, Ao X, Liang J. Identification of lactylation-related biomarkers for diagnosis, prognosis, and treatment responsiveness in triple-negative breast cancer.. World J Surg Oncol 24(1):77. 2026 Jan 22. PMID: 41566505.
[3] Wu Q, Li Z, Gong T, Zheng X, Zhou X et al.. Porphyromonas gingivalis infection induces lysine lactylation reprogramming in human umbilical vein endothelial cells.. Front Cell Infect Microbiol 16:1706727. 2026. PMID: 41696360.