Search Results

Overview

Uniprot IDQ9NUU6
Protein NameInactive ubiquitin thioesterase OTULINL
Gene NameOTULINL
OrganismHomo sapiens

Kla Sites from experimental identification

Position Flanking peptide
262 YEQMKTKKVIPSLFR

Function

Lacks deubiquitinase activity

Protein Sequence

10 MAATRSPTRA 20 RERERSGAPA 30 AGSDQVHSWM 40 LATSQALDTV 50 WRMAKGFVML 60 AVSFLVAAIC 70 YFRRLHLYSG 80 HKLKWWIGYL 90 QRKFKRNLSV 100 EAEVDLLSYC 110 AREWKGETPR 120 NKLMRKAYEE 130 LFWRHHIKCV 140 RQVRRDNYDA 150 LRSVLFQIFS 160 QGISFPSWMK 170 EKDIVKLPEK 180 LLFSQGCNWI 190 QQYSFGPEKY 200 TGSNVFGKLR 210 KYVELLKTQW 220 TEFNGIRDYH 230 KRGSMCNTLF 240 SDAILEYKLY 250 EALKFIMLYQ 260 VTEVYEQMKT 270 KKVIPSLFRL 280 LFSRETSSDP 290 LSFMMNHLNS 300 VGDTCGLEQI 310 DMFILGYSLE 320 VKIKVFRLFK 330 FNSRDFEVCY 340 PEEPLRDWPE 350 ISLLTENDRH YHIPVF

Gene Ontology

Classification GO ID Description
Cellular Component GO:0005737 cytoplasm
Cellular Component GO:0098554 cytoplasmic side of endoplasmic reticulum membrane
Cellular Component GO:0005635 nuclear envelope

Reference

[1] Yang Z, Yan C, Ma J, Peng P, Ren X et al.. Lactylome analysis suggests lactylation-dependent mechanisms of metabolic adaptation in hepatocellular carcinoma.. Nat Metab 5(1):61-79. 2023 Jan. PMID: 36593272.

[2] Wu Q, Li Z, Gong T, Zheng X, Zhou X et al.. Porphyromonas gingivalis infection induces lysine lactylation reprogramming in human umbilical vein endothelial cells.. Front Cell Infect Microbiol 16:1706727. 2026. PMID: 41696360.