Search Results
Overview
| Uniprot ID | Q9NVM6 |
|---|---|
| Protein Name | DnaJ homolog subfamily C member 17 |
| Gene Name | DNAJC17 |
| Organism | Homo sapiens |
Kla Sites from experimental identification
| Position | Flanking peptide |
|---|---|
| 264 | RSHSGLSKGSVLSER |
| 88 | QAAERTQKLDEKRKK |
| 97 | DEKRKKVKLDLEARE |
Function
May negatively affect PAX8-induced thyroglobulin/TG transcription
Protein Sequence
10
MAVTKELLQM
20
DLYALLGIEE
30
KAADKEVKKA
40
YRQKALSCHP
50
DKNPDNPRAA
60
ELFHQLSQAL
70
EVLTDAAARA
80
AYDKVRKAKK
90
QAAERTQKLD
100
EKRKKVKLDL
110
EARERQAQAQ
120
ESEEEEESRS
130
TRTLEQEIER
140
LREEGSRQLE
150
EQQRLIREQI
160
RQERDQRLRG
170
KAENTEGQGT
180
PKLKLKWKCK
190
KEDESKGGYS
200
KDVLLRLLQK
210
YGEVLNLVLS
220
SKKPGTAVVE
230
FATVKAAELA
240
VQNEVGLVDN
250
PLKISWLEGQ
260
PQDAVGRSHS
270
GLSKGSVLSE
280
RDYESLVMMR
290
MRQAAERQQL
300
IARMQQEDQE
GPPT
Gene Ontology
| Classification | GO ID | Description |
|---|---|---|
| Cellular Component | GO:0005737 | cytoplasm |
| Cellular Component | GO:0005681 | spliceosomal complex |
| Molecular Function | GO:0003723 | RNA binding |
| Biological Process | GO:0006351 | DNA-templated transcription |
| Biological Process | GO:0000390 | spliceosomal complex disassembly |
Reference
[1] Yang D, Yin J, Shan L, Yi X, Zhang W et al.. Identification of lysine-lactylated substrates in gastric cancer cells.. iScience 25(7):104630. 2022 Jul 15. PMID: 35800753.
[2] He C, Zhang J, Bai X, Lu C, Zhang K. Lysine lactylation-based insight to understanding the characterization of cervical cancer.. Biochim Biophys Acta Mol Basis Dis 1870(7):167356. 2024 Oct. PMID: 39025375.
[3] Wu Q, Li Z, Gong T, Zheng X, Zhou X et al.. Porphyromonas gingivalis infection induces lysine lactylation reprogramming in human umbilical vein endothelial cells.. Front Cell Infect Microbiol 16:1706727. 2026. PMID: 41696360.