Search Results

Overview

Uniprot IDQ9NVQ4
Protein NameFas apoptotic inhibitory molecule 1
Gene NameFAIM
OrganismHomo sapiens

Kla Sites from experimental identification

Position Flanking peptide
160 AVSSGKRKEGIIHTL

Function

Plays a role as an inducible effector molecule that mediates Fas resistance produced by surface Ig engagement in B cells

Protein Sequence

10 MTDLVAVWDV 20 ALSDGVHKIE 30 FEHGTTSGKR 40 VVYVDGKEEI 50 RKEWMFKLVG 60 KETFYVGAAK 70 TKATINIDAI 80 SGFAYEYTLE 90 INGKSLKKYM 100 EDRSKTTNTW 110 VLHMDGENFR 120 IVLEKDAMDV 130 WCNGKKLETA 140 GEFVDDGTET 150 HFSIGNHDCY 160 IKAVSSGKRK 170 EGIIHTLIVD NREIPEIAS

Gene Ontology

Classification GO ID Description
Cellular Component GO:0005737 cytoplasm
Biological Process GO:0006915 apoptotic process
Biological Process GO:1902042 negative regulation of extrinsic apoptotic signaling pathway via death domain receptors

Reference

[1] He C, Zhang J, Bai X, Lu C, Zhang K. Lysine lactylation-based insight to understanding the characterization of cervical cancer.. Biochim Biophys Acta Mol Basis Dis 1870(7):167356. 2024 Oct. PMID: 39025375.

[2] Shi CM, Wang QC, Li XL, Yang YH, Tang XY et al.. Global Profiling of Protein Lactylation in Human Hippocampi.. Proteomics Clin Appl 19(2):e202400061. 2025 Mar. PMID: 39610256.