Search Results
Overview
| Uniprot ID | Q9NVZ3 |
|---|---|
| Protein Name | Adaptin ear-binding coat-associated protein 2 |
| Gene Name | NECAP2 |
| Organism | Homo sapiens |
Kla Sites from experimental identification
| Position | Flanking peptide |
|---|---|
| 13 | YESVLCVKPDVHVYR |
| 166 | KLNIANMKKKEGAAG |
| 168 | NIANMKKKEGAAGNP |
Function
Involved in endocytosis
Protein Sequence
10
MEESGYESVL
20
CVKPDVHVYR
30
IPPRATNRGY
40
RAAEWQLDQP
50
SWSGRLRITA
60
KGQMAYIKLE
70
DRTSGELFAQ
80
APVDQFPGTA
90
VESVTDSSRY
100
FVIRIEDGNG
110
RRAFIGIGFG
120
DRGDAFDFNV
130
ALQDHFKWVK
140
QQCEFAKQAQ
150
NPDQGPKLDL
160
GFKEGQTIKL
170
NIANMKKKEG
180
AAGNPRVRPA
190
STGGLSLLPP
200
PPGGKTSTLI
210
PPPGEQLAVG
220
GSLVQPAVAP
230
SSGGAPVPWP
240
QPNPATADIW
250
GDFTKSTGST
260
SSQTQPGTGW
VQF
Gene Ontology
| Classification | GO ID | Description |
|---|---|---|
| Cellular Component | GO:0030125 | clathrin vesicle coat |
| Cellular Component | GO:0005905 | clathrin-coated pit |
| Cellular Component | GO:0005886 | plasma membrane |
| Biological Process | GO:0006897 | endocytosis |
| Biological Process | GO:0015031 | protein transport |
| Biological Process | GO:0016192 | vesicle-mediated transport |
Reference
[1] Hong H, Chen X, Wang H, Gu X, Yuan Y et al.. Global profiling of protein lysine lactylation and potential target modified protein analysis in hepatocellular carcinoma.. Proteomics 23(9):e2200432. 2023 May. PMID: 36625413.
[2] He J, Lai T, Zhou Z, Yang H, Lei Z et al.. Multiomics profiling reveals the involvement of protein lactylation in nonhomologous end joining pathway conferring radioresistance in lung adenocarcinoma cell.. Sci Rep 15(1):24651. 2025 Jul 9. PMID: 40634431.